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Table 2 Overall and cause-specific mortality by blood group in the Golestan Cohort Study

From: Mortality and cancer in relation to ABO blood group phenotypes in the Golestan Cohort Study

Blood type number (person-years) deaths (MR) Overall mortality due to medical causes a CVD mortality (number = 1,879) Cancer mortality (number = 775) Other medical causes (numner = 760)
crude HR (95% CI) adjusted HR b (95% CI) adjusted HR (95% CI) adjusted HR (95% CI) adjusted HR (95% CI)
O 14,971 (103,756) 1,007 (971) 1 1 1 1 1
A 16,705 (115,764) 1,223 (1,056) 1.11 (1.02,1.21)* 1.08 (1.00,1.18)* 1.12 (1.00,1.26)* 1.05 (0.87,1.25) 1.03 (0.86,1.23)
B 13,555 (93,740) 1,036 (1,105) 1.12 (1.03,1.23)* 1.09 (1.00,1.20)* 1.15 (1.02,1.30)* 1.14 (0.95,1.38) 0.91 (0.75,1.10)
AB 4,810 (33,434) 357 (1,068) 1.10 (0.97,1.25) 1.07 (0.95,1.22) 1.16 (0.98,1.37) 1.03 (0.79,1.35) 0.92 (0.70, 1.21)
Non-O 35,070 (242,966) 2,616 (1,077) 1.11 (1.03,1.20)* 1.09 (1.01,1.17)* 1.15 (1.03,1.27)** 1.08 (0.92,1.27) 0.97 (0.83,1.13)
Rh+ 46,803 (324,155) 3,381 (1,043) 1 1 1 1 1
Rh- 3,238 (22,553) 242 (1,073) 1.04 (0.91,1.19) 1.06 (0.93,1.21) 1.04 (0.87,1.25) 0.88 (0.64,1.19) 1.30 (0.99,1.69)
  1. aExcluding deaths due to accidents, intoxication, suicide or other types of injury; bCox regression models adjusted for age, smoking, socioeconomic status, ethnicity, residence, education, and opium use. *P <0.05, **P <0.01, CI, confidence ratio; CVD, cardiovascular disease; HR: hazard ratio; MR: mortality rate per 100,000 person-years.