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Table 6 Mortality and haemoglobin level at 8 and 24 hours by transfusion and baseline anaemia status

From: Anaemia and blood transfusion in African children presenting to hospital with severe febrile illness

  Anaemia status at baseline  
  Severe Moderate Mild No anaemia Total
Hb <5 g/dL Hb 5 to <7 g/dL Hb 7 to <10 g/dL Hb ≥10 g/dL
Status at 8 hours 1,002 501 843 736 3,082
TRANSFUSED 899 184 35 0 1,118
Hb <5 g/dL 227 (26%) 15 (8%) 2 (6%) 0 (0%) 244 (22%)
Hb 5 to <7 g/dL 347 (39%) 57 (31%) 4 (11%) 0 (0%) 408 (37%)
Hb 7 to <10 g/dL 227 (25%) 79 (43%) 16 (46%) 0 (0%) 322 (29%)
Hb ≥10 g/dL 17 (2%) 12 (7%) 3 (9%) 0 (0%) 32 (3%)
Hb missing – as died before 8 hours 39 (4%) 10 (5%) 8 (23%) 0 (0%) 57 (5%)
Hb missing – other reason 42 (5%) 11(6%) 2 (6%) 0 (0%) 54 (5%)
NOT TRANSFUSED 103 317 808 736 1,964
Hb <5 g/dL 26 (25%) 107 (34%) 14 (2%) 1 (<1%) 148 (8%)
Hb 5 to <7 g/dL 7 (7%) 51 (16%) 39 (5%) 2 (<1%) 99 (5%)
Hb 7 to <10 g/dL 4 (4%) 6 (2%) 13 (2%) 1 (<1%) 24 (1%)
Hb ≥10 g/dL 9 (9%) 128 (40%) 685 (85%) 683 (93%) 1505 (77%)
Hb missing – as died before 8 hours* 54 (52%) 12 (4%) 29 (4%) 22 (3%) 117 (6%)
Hb missing – other reason 3 (3%) 13 (4%) 28 (3%) 27 (4%) 71 (4%)
Status at 24 hours 1,002 501 843 736 3,082
TRANSFUSED 919 305 71 2 1,297
Hb <5 g/dL 143 (16%) 20 (7%) 7 (10%) 0 (0%) 170 (13%)
Hb 5 to <7 g/dL 361 (39%) 96 (31%) 12 (17%) 0 (33%) 469 (36%)
Hb 7 to <10 g/dL 293 (32%) 141 (46%) 29 (41%) 2 (67%) 465 (36%)
Hb ≥10 g/dL 31 (3%) 21 (7%) 8 (11%) 0 (0%) 60 (5%)
Hb missing – as died before 24 hours 71 (8%) 19 (6%) 13 (18%) 0 (0%) 103 (8%)
Hb missing – other reason 20 (2%) 8 (3%) 2 (3%) 0 (0%) 30 (2%)
NOT TRANSFUSED 83 196 772 734 1,785
Hb <5 g/dL 10 (12%) 26 (13%) 8 (1%) 0 (0%) 44 (2%)
Hb 5 to <7 g/dL 5 (6%) 12 (6%) 17 (2%) 2 (<1%) 36 (2%)
Hb 7 to <10 g/dL 3 (4%) 4 (2%) 5 (<1%) 0 (0%) 12 (<1%)
Hb ≥10 g/dL 7 (8%) 131 (67%) 665 (86%) 674 (92%) 1,477 (83%)
Hb missing – as died before 24 hours 57 (69%) 17 (3%) 58 (8%) 32 (4%) 164 (9%)
Hb missing – other reason 1 (1%) 6 (3%) 19 (2%) 26 (4%) 52 (3%)
  1. *90% of these children died within 2.5 hours of randomisation.