Table 1 Morphological data for the mothers and fetuses (mean ± SEM) at census date and then for those allocated to the liver and plasma cysteine and homocysteine analyses populations

Whole population at census date

N

57

66

49

56

Maternal indices

Age (years)

24 ± 1

25 ± 1

24 ± 1

24 ± 1

Body mass index (BMI) (kg/m²)

25 ± 1

25 ± 1

24 ± 1

25 ± 1

Cigarettes/day

0

11 ± 1

0

12 ± 1

Fetal indices

Age (weeks)

14.5 ± 0.3

15.1 ± 0.3

14.9 ± 0.3

14.9 ± 0.3

Weight (g)

73 ± 10^a

95 ± 9^b

87 ± 11

92 ± 12

Crown-rump length (CRL, mm)

94 ± 4^a

106 ± 4^b

101 ± 4

102 ± 4

Ponderal index (weight g/[CRL cm³])

0.067 ± 0.002

0.067 ± 0.002

0.069 ± 0.003

0.067 ± 0.002

Plasma cotinine (ng/mL)

3 ± 1^a

40 ± 2^b

4 ± 1^a

43 ± 2^b

Sub-population: methylation and metal

N

14

16

14

11

Maternal indices

Age (years)

21 ± 1

26 ± 2

25 ± 1

26 ± 2

BMI (kg/m²)

25 ± 2

26 ± 1

24 ± 1

25 ± 2

Cigarettes/day

0

16 ± 2

0

16 ± 2

Fetal indices

Age (weeks)

14.0 ± 0.6

14.3 ± 0.4

15.3 ± 0.7

15.8 ± 0.9

Weight (g)

62 ± 18

74 ± 14

100 ± 20

151 ± 34

CRL (mm)

93 ± 8

97 ± 6

103 ± 8

121 ± 9

Ponderal index (weight g/[CRL cm³])

0.063 ± 0.004

0.070 ± 0.003

0.080 ± 0.007

0.071 ± 0.003

Plasma cotinine (ng/mL)

3 ± 1^a

44 ± 3^b

3 ± 1^a

48 ± 3^b

Sub-population: plasma cysteine and homocysteine

N

14

17

13

16

Maternal indices

Age (years)

25 ± 2

24 ± 1

24 ± 2

24 ± 1

BMI (kg/m²)

26 ± 2

25 ± 2

24 ± 1

24 ± 1

Cigarettes/day

0

13 ± 1

0

11 ± 1

Fetal indices

Age (weeks)

15.2 ± 0.7

14.9 ± 0.6

15.6 ± 0.7

15.4 ± 0.6

Weight (g)

102 ± 24

89 ± 18

105 ± 21

101 ± 19

CRL (mm)

108 ± 8

105 ± 7

109 ± 8

121 ± 9

Ponderal index (weight g/[CRL cm³])

0.074 ± 0.005

0.064 ± 0.002

0.065 ± 0.003

0.065 ± 0.003

Plasma cotinine (ng/mL)

5 ± 1^a

44 ± 3^b

4 ± 3^a

41 ± 3^b