From: Seeking effective interventions to treat complex wounds: an overview of systematic reviews
Outcome | Intervention | Systematic reviews with MA | Systematic reviews without MA | ||
---|---|---|---|---|---|
High-quality* | Low/moderate quality | High-quality** | Low/moderate quality | ||
Proportion of patients with healed wounds (MAs: 1) [37] | Topical negative pressure/vacuum-assisted closure | NA | + | NA | NA |
Vacuum-assisted closure | NA | + | NA | NA | |
Alginate dressings | NA | NA | – | NA | |
Foam dressings | NA | NA | – | NA | |
Time to healing or rate of healing (MAs: NA; non-MAs: 5) [68,71,96,108,109] | Alginate dressings | NA | NA | +/− | NA |
Aloe vera dermal gel (topical) | NA | NA | +/− | NA | |
Dextranomer polysaccharide bead dressings | NA | NA | +/− | NA | |
Foam dressings | NA | NA | – | NA | |
 | Gauze + Aloe vera dressings | NA | NA | +/− | NA |
 | Honey (topical) | NA | NA |  | + |
 | Hydrocolloid dressings | NA | NA | – | NA |
 | Plaster casting | NA | NA | + | NA |
 | Polyurethane foam and sheets dressings | NA | NA | +/− | NA |
 | Silicone elastomer foam dressings and polyurethane foam dressings | NA | NA | – | NA |
 | Topical negative pressure | NA | NA | – | NA |
Dextranomer polysaccharide bead dressings | NA | NA | +/− | NA | |
Polyurethane foam dressings | NA | NA | +/− | NA |