TY - JOUR AU - White, N. J. PY - 2008 DA - 2008// TI - The role of anti-malarial drugs in eliminating malaria JO - Malar J VL - 7 UR - https://doi.org/10.1186/1475-2875-7-S1-S8 DO - 10.1186/1475-2875-7-S1-S8 ID - White2008 ER - TY - BOOK PY - 2014 DA - 2014// TI - World Malaria Report 2014 PB - World Health Organization CY - Geneva ID - ref2 ER - TY - JOUR AU - White, N. PY - 1999 DA - 1999// TI - Antimalarial drug resistance and combination chemotherapy JO - Philos Trans R Soc L B Biol Sci VL - 354 UR - https://doi.org/10.1098/rstb.1999.0426 DO - 10.1098/rstb.1999.0426 ID - White1999 ER - TY - JOUR AU - Sinclair, D. AU - Zani, B. AU - Donegan, S. AU - Olliaro, P. AU - Garner, P. PY - 2009 DA - 2009// TI - Artemisinin-based combination therapy for treating uncomplicated malaria JO - Cochrane Database Syst Rev VL - 3 ID - Sinclair2009 ER - TY - JOUR AU - Zwang, J. AU - Olliaro, P. AU - Barennes, H. AU - Bonnet, M. AU - Brasseur, P. AU - Bukirwa, H. PY - 2009 DA - 2009// TI - Efficacy of artesunate-amodiaquine for treating uncomplicated falciparum malaria in sub-Saharan Africa: a multi-centre analysis JO - Malar J VL - 8 UR - https://doi.org/10.1186/1475-2875-8-203 DO - 10.1186/1475-2875-8-203 ID - Zwang2009 ER - TY - JOUR AU - Hasugian, A. R. AU - Purba, H. L. AU - Kenangalem, E. AU - Wuwung, R. M. AU - Ebsworth, E. P. AU - Maristela, R. PY - 2007 DA - 2007// TI - Dihydroartemisinin-piperaquine versus artesunate-amodiaquine: superior efficacy and posttreatment prophylaxis against multidrug-resistant Plasmodium falciparum and Plasmodium vivax malaria JO - Clin Infect Dis VL - 44 UR - https://doi.org/10.1086/512677 DO - 10.1086/512677 ID - Hasugian2007 ER - TY - JOUR AU - Smithuis, F. AU - Kyaw, M. K. AU - Phe, O. AU - Win, T. AU - Aung, P. P. AU - Oo, A. P. P. PY - 2010 DA - 2010// TI - Effectiveness of five artemisinin combination regimens with or without primaquine in uncomplicated falciparum malaria: an open-label randomised trial JO - Lancet Infect Dis VL - 10 UR - https://doi.org/10.1016/S1473-3099(10)70187-0 DO - 10.1016/S1473-3099(10)70187-0 ID - Smithuis2010 ER - TY - JOUR AU - Adjuik, M. AU - Agnamey, P. AU - Babiker, A. AU - Borrmann, S. AU - Brasseur, P. AU - Cisse, M. PY - 2002 DA - 2002// TI - Amodiaquine-artesunate versus amodiaquine for uncomplicated Plasmodium falciparum malaria in African children: a randomised, multicentre trial JO - Lancet VL - 359 UR - https://doi.org/10.1016/S0140-6736(02)08348-4 DO - 10.1016/S0140-6736(02)08348-4 ID - Adjuik2002 ER - TY - JOUR AU - Mutabingwa, T. K. AU - Anthony, D. AU - Heller, A. AU - Hallett, R. AU - Ahmed, J. AU - Drakeley, C. PY - 2005 DA - 2005// TI - Amodiaquine alone, amodiaquine + sulfadoxine-pyrimethamine, amodiaquine + artesunate, and artemether-lumefantrine for outpatient treatment of malaria in Tanzanian children: a four-arm randomised effectiveness trial JO - Lancet VL - 365 UR - https://doi.org/10.1016/S0140-6736(05)66417-3 DO - 10.1016/S0140-6736(05)66417-3 ID - Mutabingwa2005 ER - TY - JOUR AU - Bonnet, M. AU - Broek, I. AU - Herp, M. AU - Urrutia, P. P. AU - Overmeir, C. AU - Kyomuhendo, J. PY - 2009 DA - 2009// TI - Varying efficacy of artesunate + amodiaquine and artesunate + sulphadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in the Democratic Republic of Congo: a report of two in-vivo studies JO - Malar J VL - 8 UR - https://doi.org/10.1186/1475-2875-8-192 DO - 10.1186/1475-2875-8-192 ID - Bonnet2009 ER - TY - JOUR AU - Rwagacondo, C. E. AU - Karema, C. AU - Mugisha, V. AU - Erhart, A. AU - Dujardin, J. C. AU - Overmeir, C. PY - 2004 DA - 2004// TI - Is amodiaquine failing in Rwanda? Efficacy of amodiaquine alone and combined with artesunate in children with uncomplicated malaria JO - Trop Med Int Health VL - 9 UR - https://doi.org/10.1111/j.1365-3156.2004.01316.x DO - 10.1111/j.1365-3156.2004.01316.x ID - Rwagacondo2004 ER - TY - JOUR AU - Alifrangis, M. AU - Dalgaard, M. B. AU - Lusingu, J. P. AU - Vestergaard, L. S. AU - Staalsoe, T. AU - Jensen, A. T. PY - 2006 DA - 2006// TI - Occurrence of the Southeast Asian/South American SVMNT haplotype of the chloroquine-resistance transporter gene in Plasmodium falciparum in Tanzania JO - J Infect Dis VL - 193 UR - https://doi.org/10.1086/504269 DO - 10.1086/504269 ID - Alifrangis2006 ER - TY - JOUR AU - Sa, J. M. AU - Twu, O. PY - 2010 DA - 2010// TI - Protecting the malaria drug arsenal: halting the rise and spread of amodiaquine resistance by monitoring the PfCRT SVMNT type JO - Malar J VL - 9 UR - https://doi.org/10.1186/1475-2875-9-374 DO - 10.1186/1475-2875-9-374 ID - Sa2010 ER - TY - JOUR AU - Sa, J. M. AU - Twu, O. AU - Hayton, K. AU - Reyes, S. AU - Fay, M. P. AU - Ringwald, P. PY - 2009 DA - 2009// TI - Geographic patterns of Plasmodium falciparum drug resistance distinguished by differential responses to amodiaquine and chloroquine JO - Proc Natl Acad Sci U S A VL - 106 UR - https://doi.org/10.1073/pnas.0911317106 DO - 10.1073/pnas.0911317106 ID - Sa2009 ER - TY - STD TI - The Four Artemisinin-Based Combinations (4ABC) Study Group. A head-to-head comparison of four artemisinin-based combinations for treating uncomplicated malaria in African children: a randomized trial. PLoS Med. 2011;8:e1001119. ID - ref15 ER - TY - JOUR AU - Thanh, N. X. AU - Trung, T. N. AU - Phong, N. C. AU - Quang, H. H. AU - Dai, B. AU - Shanks, G. D. PY - 2012 DA - 2012// TI - The efficacy and tolerability of artemisinin-piperaquine (Artequick(R)) versus artesunate-amodiaquine (Coarsucam) for the treatment of uncomplicated Plasmodium falciparum malaria in south-central Vietnam JO - Malar J VL - 11 UR - https://doi.org/10.1186/1475-2875-11-217 DO - 10.1186/1475-2875-11-217 ID - Thanh2012 ER - TY - JOUR AU - Brasseur, P. AU - Agnamey, P. AU - Gaye, O. AU - Cisse, M. AU - Badiane, M. AU - Vaillant, M. PY - 2009 DA - 2009// TI - Dosing accuracy of artesunate and amodiaquine as treatment for falciparum malaria in Casamance, Senegal JO - Trop Med Int Health VL - 14 UR - https://doi.org/10.1111/j.1365-3156.2008.02190.x DO - 10.1111/j.1365-3156.2008.02190.x ID - Brasseur2009 ER - TY - JOUR AU - Sirima, S. B. AU - Tiono, A. B. AU - Gansane, A. AU - Diarra, A. AU - Ouedraogo, A. AU - Konate, A. T. PY - 2009 DA - 2009// TI - The efficacy and safety of a new fixed-dose combination of amodiaquine and artesunate in young African children with acute uncomplicated Plasmodium falciparum JO - Malar J VL - 8 UR - https://doi.org/10.1186/1475-2875-8-48 DO - 10.1186/1475-2875-8-48 ID - Sirima2009 ER - TY - STD TI - Clinical trials review. http://www.wwarn.org/tools-resources/literature-reviews/wwarn-clinical-trials-publication-library/methodology. UR - http://www.wwarn.org/tools-resources/literature-reviews/wwarn-clinical-trials-publication-library/methodology ID - ref19 ER - TY - STD TI - WWARN DP Study Group TWARN (WWARN) DS Group: The effect of dosing regimens on the antimalarial efficacy of dihydroartemisinin-piperaquine: a pooled analysis of individual patient data. PLoS Med. 2013, 10:e1001564. doi:10.1371/journal.pmed.1001564. ID - ref20 ER - TY - JOUR AU - Gething, P. W. AU - Patil, A. P. AU - Smith, D. L. AU - Guerra, C. A. AU - Elyazar, I. R. AU - Johnston, G. L. PY - 2011 DA - 2011// TI - A new world malaria map: Plasmodium falciparum endemicity in 2010 JO - Malar J VL - 10 UR - https://doi.org/10.1186/1475-2875-10-378 DO - 10.1186/1475-2875-10-378 ID - Gething2011 ER - TY - STD TI - WWARN: Statistical Analysis Plan, AS-AQ Dose Impact Study Group. Version 1.9. WordlWide Antimalarial Resistance Network, Oxford, 2012. ID - ref22 ER - TY - STD TI - WWARN. Clinical Module: Data Management and Statistical Analysis Plan. Version 1.2. WorldWide Antimalarial Resistance Network, Oxford, 2012. ID - ref23 ER - TY - JOUR AU - Glidden, D. V. AU - Vittinghoff, E. PY - 2004 DA - 2004// TI - Modelling clustered survival data from multicentre clinical trials JO - Stat Med VL - 23 UR - https://doi.org/10.1002/sim.1599 DO - 10.1002/sim.1599 ID - Glidden2004 ER - TY - JOUR AU - Munda, M. AU - Legrand, C. PY - 2014 DA - 2014// TI - Adjusting for centre heterogeneity in multicentre clinical trials with a time-to-event outcome JO - Pharm Stat VL - 13 UR - https://doi.org/10.1002/pst.1612 DO - 10.1002/pst.1612 ID - Munda2014 ER - TY - JOUR AU - Levin, M. L. PY - 1953 DA - 1953// TI - The occurrence of lung cancer in man JO - Acta Unio Int Contra Cancrum VL - 9 ID - Levin1953 ER - TY - STD TI - Guidelines for the treatment of malaria, 2nd ed. http://www.who.int/malaria/publications/atoz/9789241547925/en/ UR - http://www.who.int/malaria/publications/atoz/9789241547925/en/ ID - ref27 ER - TY - JOUR AU - Price, R. AU - Luxemburger, C. AU - Vugt, M. AU - Nosten, F. AU - Kham, A. AU - Simpson, J. PY - 1998 DA - 1998// TI - Artesunate and mefloquine in the treatment of uncomplicated multidrug-resistant hyperparasitaemic falciparum malaria JO - Trans R Soc Trop Med Hyg VL - 92 UR - https://doi.org/10.1016/S0035-9203(98)90750-7 DO - 10.1016/S0035-9203(98)90750-7 ID - Price1998 ER - TY - JOUR AU - Nacher, M. AU - Carrara, V. I. AU - Ashley, E. AU - McGready, R. AU - Hutagalung, R. AU - Nguen, J. V. PY - 2004 DA - 2004// TI - Seasonal variation in hyperparasitaemia and gametocyte carriage in patients with Plasmodium falciparum malaria on the Thai-Burmese border JO - Trans R Soc Trop Med Hyg VL - 98 UR - https://doi.org/10.1016/j.trstmh.2003.10.005 DO - 10.1016/j.trstmh.2003.10.005 ID - Nacher2004 ER - TY - JOUR AU - Ndiaye, J. L. AU - Randrianarivelojosia, M. AU - Sagara, I. AU - Brasseur, P. AU - Ndiaye, I. AU - Faye, B. PY - 2009 DA - 2009// TI - Randomized, multicentre assessment of the efficacy and safety of ASAQ - a fixed-dose artesunate-amodiaquine combination therapy in the treatment of uncomplicated Plasmodium falciparum malaria JO - Malar J VL - 8 UR - https://doi.org/10.1186/1475-2875-8-125 DO - 10.1186/1475-2875-8-125 ID - Ndiaye2009 ER - TY - JOUR AU - Sinou, V. AU - Malaika, L. T. AU - Taudon, N. AU - Lwango, R. AU - Alegre, S. S. AU - Bertaux, L. PY - 2009 DA - 2009// TI - Pharmacokinetics and pharmacodynamics of a new ACT formulation: Artesunate/Amodiaquine (TRIMALACT) following oral administration in African malaria patients JO - Eur J Drug Metab Pharmacokinet VL - 34 UR - https://doi.org/10.1007/BF03191163 DO - 10.1007/BF03191163 ID - Sinou2009 ER - TY - JOUR AU - Ndiaye, J. L. AU - Faye, B. AU - Gueye, A. AU - Tine, R. AU - Ndiaye, D. AU - Tchania, C. PY - 2011 DA - 2011// TI - Repeated treatment of recurrent uncomplicated Plasmodium falciparum malaria in Senegal with fixed-dose artesunate plus amodiaquine versus fixed-dose artemether plus lumefantrine: a randomized, open-label trial JO - Malar J VL - 10 UR - https://doi.org/10.1186/1475-2875-10-237 DO - 10.1186/1475-2875-10-237 ID - Ndiaye2011 ER - TY - JOUR AU - Hoz, R. F. AU - Porras Ramirez, A. AU - Rico Mendoza, A. AU - Cordoba, F. AU - Rojas, D. P. PY - 2012 DA - 2012// TI - Artesunate + amodiaquine versus artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in the Colombian Pacific region: a noninferiority trial JO - Rev Soc Bras Med Trop VL - 45 UR - https://doi.org/10.1590/S0037-86822012000600015 DO - 10.1590/S0037-86822012000600015 ID - Hoz2012 ER - TY - JOUR AU - Espie, E. AU - Lima, A. AU - Atua, B. AU - Dhorda, M. AU - Flevaud, L. AU - Sompwe, E. M. PY - 2012 DA - 2012// TI - Efficacy of fixed-dose combination artesunate-amodiaquine versus artemether-lumefantrine for uncomplicated childhood Plasmodium falciparum malaria in Democratic Republic of Congo: a randomized non-inferiority trial JO - Malar J VL - 11 UR - https://doi.org/10.1186/1475-2875-11-174 DO - 10.1186/1475-2875-11-174 ID - Espie2012 ER - TY - JOUR AU - Faye, B. AU - Kuete, T. AU - Kiki-Barro, C. P. AU - Tine, R. C. AU - Nkoa, T. AU - Ndiaye, J. L. PY - 2012 DA - 2012// TI - Multicentre study evaluating the non-inferiority of the new paediatric formulation of artesunate/amodiaquine versus artemether/lumefantrine for the management of uncomplicated Plasmodium falciparum malaria in children in Cameroon, Ivory Coast and Senegal JO - Malar J VL - 11 UR - https://doi.org/10.1186/1475-2875-11-433 DO - 10.1186/1475-2875-11-433 ID - Faye2012 ER - TY - JOUR AU - Anvikar, A. R. AU - Sharma, B. AU - Shahi, B. H. AU - Tyagi, P. K. AU - Bose, T. K. AU - Sharma, S. K. PY - 2012 DA - 2012// TI - Artesunate-amodiaquine fixed dose combination for the treatment of Plasmodium falciparum malaria in India JO - Malar J VL - 11 UR - https://doi.org/10.1186/1475-2875-11-97 DO - 10.1186/1475-2875-11-97 ID - Anvikar2012 ER - TY - JOUR AU - Ndounga, M. AU - Mayengue, P. I. AU - Casimiro, P. N. AU - Loumouamou, D. AU - Basco, L. K. AU - Ntoumi, F. PY - 2013 DA - 2013// TI - Artesunate-amodiaquine efficacy in Congolese children with acute uncomplicated falciparum malaria in Brazzaville JO - Malar J VL - 12 UR - https://doi.org/10.1186/1475-2875-12-53 DO - 10.1186/1475-2875-12-53 ID - Ndounga2013 ER - TY - JOUR AU - Schramm, B. AU - Valeh, P. AU - Baudin, E. AU - Mazinda, C. S. AU - Smith, R. AU - Pinoges, L. PY - 2013 DA - 2013// TI - Efficacy of artesunate-amodiaquine and artemether-lumefantrine fixed-dose combinations for the treatment of uncomplicated Plasmodium falciparum malaria among children aged six to 59 months in Nimba County, Liberia: an open-label randomized non-inferiority JO - Malar J VL - 12 UR - https://doi.org/10.1186/1475-2875-12-251 DO - 10.1186/1475-2875-12-251 ID - Schramm2013 ER - TY - JOUR AU - Elliott, I. AU - Mayxay, M. AU - Yeuichaixong, S. AU - Lee, S. J. AU - Newton, P. N. PY - 2014 DA - 2014// TI - The practice and clinical implications of tablet splitting in international health JO - Trop Med Int Health VL - 19 UR - https://doi.org/10.1111/tmi.12309 DO - 10.1111/tmi.12309 ID - Elliott2014 ER - TY - JOUR AU - Taylor, W. AU - Terlouw, D. J. AU - Olliaro, P. L. AU - White, N. J. AU - Brasseur, P. AU - Kuile, F. O. PY - 2006 DA - 2006// TI - Use of weight-for-age-data to optimize tablet strength and dosing regimens for a new fixed-dose artesunate-amodiaquine combination for treating falciparum malaria JO - Bull World Health Organ VL - 84 UR - https://doi.org/10.2471/BLT.06.031492 DO - 10.2471/BLT.06.031492 ID - Taylor2006 ER - TY - JOUR AU - Connor, J. AU - Rafter, N. AU - Rodgers, A. PY - 2004 DA - 2004// TI - Do fixed-dose combination pills or unit-of-use packaging improve adherence? A systematic review JO - Bull World Health Organ VL - 82 ID - Connor2004 ER - TY - STD TI - Amodiaquine PK/PD Study Group. http://www.wwarn.org/working-together/study-groups/amodiaquine-pkpd-study-group UR - http://www.wwarn.org/working-together/study-groups/amodiaquine-pkpd-study-group ID - ref42 ER - TY - JOUR AU - Eyase, F. L. AU - Akala, H. M. AU - Ingasia, L. AU - Cheruiyot, A. AU - Omondi, A. AU - Okudo, C. PY - 2013 DA - 2013// TI - The role of Pfmdr1 and Pfcrt in changing chloroquine, amodiaquine, mefloquine and lumefantrine susceptibility in western-Kenya P. falciparum samples during 2008-2011 JO - PLoS One VL - 8 UR - https://doi.org/10.1371/journal.pone.0064299 DO - 10.1371/journal.pone.0064299 ID - Eyase2013 ER - TY - JOUR AU - Grandesso, F. AU - Hagerman, A. AU - Kamara, S. AU - Lam, E. AU - Checchi, F. AU - Balkan, S. PY - 2006 DA - 2006// TI - Low efficacy of the combination artesunate plus amodiaquine for uncomplicated falciparum malaria among children under 5 years in Kailahun, Sierra Leone JO - Trop Med Int Health VL - 11 UR - https://doi.org/10.1111/j.1365-3156.2006.01655.x DO - 10.1111/j.1365-3156.2006.01655.x ID - Grandesso2006 ER - TY - JOUR AU - Martensson, A. AU - Stromberg, J. AU - Sisowath, C. AU - Msellem, M. I. AU - Gil, J. P. AU - Montgomery, S. M. PY - 2005 DA - 2005// TI - Efficacy of artesunate plus amodiaquine versus that of artemether-lumefantrine for the treatment of uncomplicated childhood Plasmodium falciparum malaria in Zanzibar, Tanzania JO - Clin Infect Dis VL - 41 UR - https://doi.org/10.1086/444460 DO - 10.1086/444460 ID - Martensson2005 ER - TY - JOUR AU - Thwing, J. I. AU - Odero, C. O. AU - Odhiambo, F. O. AU - Otieno, K. O. AU - Kariuki, S. AU - Ord, R. PY - 2009 DA - 2009// TI - In-vivo efficacy of amodiaquine-artesunate in children with uncomplicated Plasmodium falciparum malaria in western Kenya JO - Trop Med Int Health VL - 14 UR - https://doi.org/10.1111/j.1365-3156.2009.02222.x DO - 10.1111/j.1365-3156.2009.02222.x ID - Thwing2009 ER - TY - JOUR AU - Ochong, E. O. AU - Broek, I. V. AU - Keus, K. AU - Nzila, A. PY - 2003 DA - 2003// TI - Short report: association between chloroquine and amodiaquine resistance and allelic variation in the Plasmodium falciparum multiple drug resistance 1 gene and the chloroquine resistance transporter gene in isolates from the upper Nile in southern Sudan JO - Am J Trop Med Hyg VL - 69 ID - Ochong2003 ER - TY - JOUR AU - Happi, C. T. AU - Gbotosho, G. O. AU - Folarin, O. A. AU - Bolaji, O. M. AU - Sowunmi, A. AU - Kyle, D. E. PY - 2006 DA - 2006// TI - Association between mutations in Plasmodium falciparum chloroquine resistance transporter and P. falciparum multidrug resistance 1 genes and in vivo amodiaquine resistance in P. falciparum malaria-infected children in Nigeria JO - Am J Trop Med Hyg VL - 75 ID - Happi2006 ER - TY - JOUR AU - Echeverry, D. F. AU - Holmgren, G. AU - Murillo, C. AU - Higuita, J. C. AU - Bjorkman, A. AU - Gil, J. P. PY - 2007 DA - 2007// TI - Short report: polymorphisms in the pfcrt and pfmdr1 genes of Plasmodium falciparum and in vitro susceptibility to amodiaquine and desethylamodiaquine JO - Am J Trop Med Hyg VL - 77 ID - Echeverry2007 ER - TY - JOUR AU - Nsobya, S. L. AU - Dokomajilar, C. AU - Joloba, M. AU - Dorsey, G. AU - Rosenthal, P. J. PY - 2007 DA - 2007// TI - Resistance-mediating Plasmodium falciparum pfcrt and pfmdr1 alleles after treatment with artesunate-amodiaquine in Uganda JO - Antimicrob Agents Chemother VL - 51 UR - https://doi.org/10.1128/AAC.00012-07 DO - 10.1128/AAC.00012-07 ID - Nsobya2007 ER - TY - JOUR AU - Holmgren, G. AU - Hamrin, J. AU - Svard, J. AU - Martensson, A. AU - Gil, J. P. AU - Bjorkman, A. PY - 2007 DA - 2007// TI - Selection of pfmdr1 mutations after amodiaquine monotherapy and amodiaquine plus artemisinin combination therapy in East Africa JO - Infect Genet Evol VL - 7 UR - https://doi.org/10.1016/j.meegid.2007.03.005 DO - 10.1016/j.meegid.2007.03.005 ID - Holmgren2007 ER - TY - JOUR AU - Danquah, I. AU - Coulibaly, B. AU - Meissner, P. AU - Petruschke, I. AU - Muller, O. AU - Mockenhaupt, F. P. PY - 2010 DA - 2010// TI - Selection of pfmdr1 and pfcrt alleles in amodiaquine treatment failure in north-western Burkina Faso JO - Acta Trop VL - 114 UR - https://doi.org/10.1016/j.actatropica.2009.12.008 DO - 10.1016/j.actatropica.2009.12.008 ID - Danquah2010 ER - TY - JOUR AU - Dittrich, S. AU - Alifrangis, M. AU - Stohrer, J. M. AU - Thongpaseuth, V. AU - Vanisaveth, V. AU - Phetsouvanh, R. PY - 2005 DA - 2005// TI - Falciparum malaria in the north of Laos: the occurrence and implications of the Plasmodium falciparum chloroquine resistance transporter (pfcrt) gene haplotype SVMNT JO - Trop Med Int Health VL - 10 UR - https://doi.org/10.1111/j.1365-3156.2005.01514.x DO - 10.1111/j.1365-3156.2005.01514.x ID - Dittrich2005 ER - TY - JOUR AU - Beshir, K. AU - Sutherland, C. J. AU - Merinopoulos, I. AU - Durrani, N. AU - Leslie, T. AU - Rowland, M. PY - 2010 DA - 2010// TI - Amodiaquine resistance in Plasmodium falciparum malaria in Afghanistan is associated with the pfcrt SVMNT allele at codons 72 to 76 JO - Antimicrob Agents Chemother VL - 54 UR - https://doi.org/10.1128/AAC.00358-10 DO - 10.1128/AAC.00358-10 ID - Beshir2010 ER - TY - JOUR AU - Bukirwa, H. AU - Yeka, A. AU - Kamya, M. R. AU - Talisuna, A. AU - Banek, K. AU - Bakyaita, N. PY - 2006 DA - 2006// TI - Artemisinin combination therapies for treatment of uncomplicated malaria in Uganda JO - PLoS Clin Trials VL - 1 UR - https://doi.org/10.1371/journal.pctr.0010007 DO - 10.1371/journal.pctr.0010007 ID - Bukirwa2006 ER - TY - JOUR AU - Thanh, N. X. AU - Trung, T. N. AU - Phong, N. C. AU - Thien, N. X. AU - Dai, B. AU - Shanks, G. D. PY - 2009 DA - 2009// TI - Open label randomized comparison of dihydroartemisinin-piperaquine and artesunate-amodiaquine for the treatment of uncomplicated Plasmodium falciparum malaria in central Vietnam JO - Trop Med Int Heal VL - 14 UR - https://doi.org/10.1111/j.1365-3156.2009.02269.x DO - 10.1111/j.1365-3156.2009.02269.x ID - Thanh2009 ER - TY - JOUR AU - Hatton, C. S. AU - Peto, T. E. AU - Bunch, C. AU - Pasvol, G. AU - Russell, S. J. AU - Singer, C. R. PY - 1986 DA - 1986// TI - Frequency of severe neutropenia associated with amodiaquine prophylaxis against malaria JO - Lancet VL - 1 UR - https://doi.org/10.1016/S0140-6736(86)92371-8 DO - 10.1016/S0140-6736(86)92371-8 ID - Hatton1986 ER - TY - JOUR AU - Gasasira, A. F. AU - Kamya, M. R. AU - Achan, J. AU - Mebrahtu, T. AU - Kalyango, J. N. AU - Ruel, T. PY - 2008 DA - 2008// TI - High risk of neutropenia in HIV-infected children following treatment with artesunate plus amodiaquine for uncomplicated malaria in Uganda JO - Clin Infect Dis VL - 46 UR - https://doi.org/10.1086/529192 DO - 10.1086/529192 ID - Gasasira2008 ER - TY - STD TI - WWARN AL Study Group TWARNA Dose Impact S Group. The effect of dose on the antimalarial efficacy of artemether-lumefantrine: a pooled analysis of individual patient data. Lancet Infect Dis. 2015; In press. ID - ref59 ER - TY - STD TI - WHO List of Prequalified Medicinal Products. http://apps.who.int/prequal/query/ProductRegistry.aspx. UR - http://apps.who.int/prequal/query/ProductRegistry.aspx ID - ref60 ER - TY - JOUR AU - Ecker, A. AU - Lehane, A. M. AU - Clain, J. AU - Fidock, D. A. PY - 2012 DA - 2012// TI - PfCRT and its role in antimalarial drug resistance JO - Trends Parasitol VL - 28 UR - https://doi.org/10.1016/j.pt.2012.08.002 DO - 10.1016/j.pt.2012.08.002 ID - Ecker2012 ER - TY - JOUR AU - Rosenthal, P. J. PY - 2013 DA - 2013// TI - The interplay between drug resistance and fitness in malaria parasites JO - Mol Microbiol VL - 89 UR - https://doi.org/10.1111/mmi.12349 DO - 10.1111/mmi.12349 ID - Rosenthal2013 ER - TY - JOUR AU - Ariey, F. AU - Witkowski, B. AU - Amaratunga, C. AU - Beghain, J. AU - Langlois, A. -. C. AU - Khim, N. PY - 2014 DA - 2014// TI - A molecular marker of artemisinin-resistant Plasmodium falciparum malaria JO - Nature VL - 505 UR - https://doi.org/10.1038/nature12876 DO - 10.1038/nature12876 ID - Ariey2014 ER - TY - JOUR AU - Barennes, H. AU - Nagot, N. AU - Valea, I. AU - Koussoube-Balima, T. AU - Ouedraogo, A. AU - Sanou, T. PY - 2004 DA - 2004// TI - A randomized trial of amodiaquine and artesunate alone and in combination for the treatment of uncomplicated falciparum malaria in children from Burkina Faso JO - Trop Med Int Heal VL - 9 UR - https://doi.org/10.1111/j.1365-3156.2004.01224.x DO - 10.1111/j.1365-3156.2004.01224.x ID - Barennes2004 ER - TY - JOUR AU - Bonnet, M. AU - Roper, C. AU - Félix, M. AU - Coulibaly, L. AU - Kankolongo, G. M. AU - Guthmann, J. P. PY - 2007 DA - 2007// TI - Efficacy of antimalarial treatment in Guinea: in vivo study of two artemisinin combination therapies in Dabola and molecular markers of resistance to sulphadoxine-pyrimethamine in N’Zérékoré JO - Malar J VL - 6 UR - https://doi.org/10.1186/1475-2875-6-54 DO - 10.1186/1475-2875-6-54 ID - Bonnet2007 ER - TY - JOUR AU - Bukirwa, H. AU - Critchley, J. PY - 2006 DA - 2006// TI - Sulfadoxine-pyrimethamine plus artesunate versus sulfadoxine-pyrimethamine plus amodiaquine for treating uncomplicated malaria JO - Cochrane Database Syst Rev VL - 1 ID - Bukirwa2006 ER - TY - JOUR AU - Dorsey, G. AU - Staedke, S. AU - Clark, T. D. AU - Njama-Meya, D. AU - Nzarubara, B. AU - Maiteki-Sebuguzi, C. PY - 2007 DA - 2007// TI - Combination therapy for uncomplicated falciparum malaria in Ugandan children: a randomized trial JO - JAMA VL - 297 UR - https://doi.org/10.1001/jama.297.20.2210 DO - 10.1001/jama.297.20.2210 ID - Dorsey2007 ER - TY - JOUR AU - Faucher, J. F. AU - Aubouy, A. AU - Adeothy, A. AU - Cottrell, G. AU - Doritchamou, J. AU - Gourmel, B. PY - 2009 DA - 2009// TI - Comparison of sulfadoxine-pyrimethamine, unsupervised artemether-lumefantrine, and unsupervised artesunate-amodiaquine fixed-dose formulation for uncomplicated plasmodium falciparum malaria in Benin: a randomized effectiveness noninferiority trial JO - J Infect Dis VL - 200 UR - https://doi.org/10.1086/599378 DO - 10.1086/599378 ID - Faucher2009 ER - TY - JOUR AU - Faye, B. AU - Offianan, A. T. AU - Ndiaye, J. L. AU - Tine, R. C. AU - Toure, W. AU - Djoman, K. PY - 2010 DA - 2010// TI - Efficacy and tolerability of artesunate-amodiaquine (Camoquin plus) versus artemether-lumefantrine (Coartem) against uncomplicated Plasmodium falciparum malaria: multisite trial in Senegal and Ivory Coast JO - Trop Med Int Health VL - 15 ID - Faye2010 ER - TY - JOUR AU - Guthmann, J. P. AU - Ampuero, J. AU - Fortes, F. AU - Overmeir, C. AU - Gaboulaud, V. AU - Tobback, S. PY - 2005 DA - 2005// TI - Antimalarial efficacy of chloroquine, amodiaquine, sulfadoxine-pyrimethamine, and the combinations of amodiaquine + artesunate and sulfadoxine-pyrimethamine + artesunate in Huambo and Bie provinces, central Angola JO - Trans R Soc Trop Med Hyg VL - 99 UR - https://doi.org/10.1016/j.trstmh.2004.11.010 DO - 10.1016/j.trstmh.2004.11.010 ID - Guthmann2005 ER - TY - JOUR AU - Guthmann, J. P. AU - Cohuet, S. AU - Rigutto, C. AU - Fortes, F. AU - Saraiva, N. AU - Kiguli, J. PY - 2006 DA - 2006// TI - High efficacy of two artemisinin-based combinations (artesunate + amodiaquine and artemether + lumefantrine) in Caala, Central Angola JO - Am J Trop Med Hyg VL - 75 ID - Guthmann2006 ER - TY - JOUR AU - Hamour, S. AU - Melaku, Y. AU - Keus, K. AU - Wambugu, J. AU - Atkin, S. AU - Montgomery, J. PY - 2005 DA - 2005// TI - Malaria in the Nuba Mountains of Sudan: baseline genotypic resistance and efficacy of the artesunate plus sulfadoxine-pyrimethamine and artesunate plus amodiaquine combinations JO - Trans R Soc Trop Med Hyg VL - 99 UR - https://doi.org/10.1016/j.trstmh.2004.10.003 DO - 10.1016/j.trstmh.2004.10.003 ID - Hamour2005 ER - TY - JOUR AU - Jullien, V. AU - Ogutu, B. AU - Juma, E. AU - Carn, G. AU - Obonyo, C. AU - Kiechel, J. R. PY - 2010 DA - 2010// TI - Population pharmacokinetics and pharmacodynamic considerations of amodiaquine and desethylamodiaquine in Kenyan adults with uncomplicated malaria receiving artesunate-amodiaquine combination therapy JO - Antimicrob Agents Chemother VL - 54 UR - https://doi.org/10.1128/AAC.01496-09 DO - 10.1128/AAC.01496-09 ID - Jullien2010 ER - TY - JOUR AU - Karema, C. AU - Fanello, C. I. AU - Overmeir, C. AU - Geertruyden, J. P. AU - Doren, W. AU - Ngamije, D. PY - 2006 DA - 2006// TI - Safety and efficacy of dihydroartemisinin/piperaquine (Artekin) for the treatment of uncomplicated Plasmodium falciparum malaria in Rwandan children JO - Trans R Soc Trop Med Hyg VL - 100 UR - https://doi.org/10.1016/j.trstmh.2006.01.001 DO - 10.1016/j.trstmh.2006.01.001 ID - Karema2006 ER - TY - JOUR AU - Kayentao, K. AU - Maiga, H. AU - Newman, R. D. AU - McMorrow, M. L. AU - Hoppe, A. AU - Yattara, O. PY - 2009 DA - 2009// TI - Artemisinin-based combinations versus amodiaquine plus sulphadoxine-pyrimethamine for the treatment of uncomplicated malaria in Faladje, Mali JO - Malar J VL - 8 UR - https://doi.org/10.1186/1475-2875-8-5 DO - 10.1186/1475-2875-8-5 ID - Kayentao2009 ER - TY - JOUR AU - Ménard, D. AU - Ratsimbasoa, A. AU - Randrianarivelojosia, M. AU - Rabarijaona, L. -. P. AU - Raharimalala, L. AU - Domarle, O. PY - 2008 DA - 2008// TI - Assessment of the efficacy of antimalarial drugs recommended by the National Malaria Control Programme in Madagascar: up-dated baseline data from randomized and multi-site clinical trials JO - Malar J VL - 7 UR - https://doi.org/10.1186/1475-2875-7-55 DO - 10.1186/1475-2875-7-55 ID - Ménard2008 ER - TY - JOUR AU - Osorio, L. AU - Gonzalez, I. AU - Olliaro, P. AU - Taylor, W. R. PY - 2007 DA - 2007// TI - Artemisinin-based combination therapy for uncomplicated Plasmodium falciparum malaria in Colombia JO - Malar J VL - 6 UR - https://doi.org/10.1186/1475-2875-6-25 DO - 10.1186/1475-2875-6-25 ID - Osorio2007 ER - TY - JOUR AU - Sagara, I. AU - Fofana, B. AU - Gaudart, J. AU - Sidibe, B. AU - Togo, A. AU - Toure, S. PY - 2012 DA - 2012// TI - Repeated artemisinin-based combination therapies in a malaria hyperendemic area of Mali: efficacy, safety, and public health impact JO - Am J Trop Med Hyg VL - 87 UR - https://doi.org/10.4269/ajtmh.2012.11-0649 DO - 10.4269/ajtmh.2012.11-0649 ID - Sagara2012 ER - TY - JOUR AU - Staedke, S. G. AU - Mpimbaza, A. AU - Kamya, M. R. AU - Nzarubara, B. K. AU - Dorsey, G. AU - Rosenthal, P. J. PY - 2004 DA - 2004// TI - Combination treatments for uncomplicated falciparum malaria in Kampala, Uganda: randomised clinical trial JO - Lancet VL - 364 UR - https://doi.org/10.1016/S0140-6736(04)17478-3 DO - 10.1016/S0140-6736(04)17478-3 ID - Staedke2004 ER - TY - JOUR AU - Swarthout, T. D. AU - Broek, I. V. AU - Kayembe, G. AU - Montgomery, J. AU - Pota, H. AU - Roper, C. PY - 2006 DA - 2006// TI - Artesunate + amodiaquine and artesunate + sulphadoxine-pyrimethamine for treatment of uncomplicated malaria in Democratic Republic of Congo: a clinical trial with determination of sulphadoxine and pyrimethamine-resistant haplotypes JO - Trop Med Int Health VL - 11 UR - https://doi.org/10.1111/j.1365-3156.2006.01710.x DO - 10.1111/j.1365-3156.2006.01710.x ID - Swarthout2006 ER - TY - JOUR AU - Broek, I. AU - Kitz, C. AU - Al Attas, S. AU - Libama, F. AU - Balasegaram, M. AU - Guthmann, J. -. P. PY - 2006 DA - 2006// TI - Efficacy of three artemisinin combination therapies for the treatment of uncomplicated Plasmodium falciparum malaria in the Republic of Congo JO - Malar J VL - 5 UR - https://doi.org/10.1186/1475-2875-5-113 DO - 10.1186/1475-2875-5-113 ID - Broek2006 ER - TY - JOUR AU - Yeka, A. AU - Banek, K. AU - Bakyaita, N. AU - Staedke, S. G. AU - Kamya, M. R. AU - Talisuna, A. PY - 2005 DA - 2005// TI - Artemisinin versus nonartemisinin combination therapy for uncomplicated malaria: randomized clinical trials from four sites in Uganda JO - PLoS Med VL - 2 UR - https://doi.org/10.1371/journal.pmed.0020190 DO - 10.1371/journal.pmed.0020190 ID - Yeka2005 ER -