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Table 2 TB incidence rates during ART stratified according to time-updated anaemia severity and CD4 cell count

From: The predictive value of current haemoglobin levels for incident tuberculosis and/or mortality during long-term antiretroviral therapy in South Africa: a cohort study

  Overall TB incidence TB incidence in first 4 months of ART TB incidence after 4 months of ART
  Total number PY at risk Rate per 100 Total number PY at risk* Rate per 100 Total number PY at risk* Rate per 100
PYs (95%CI) PYs (95%CI) PYs (95%CI)
Updated WHO Anaemia severity          
None 183 4,199.9 4.4 (3.8-5.1) 17 101.4 16.8 (10.6-28.2) 166 4,098.5 4.1 (3.5-4.7)
Mild 113 1,131.0 10.0 (8.3-12.1) 23 85.1 27.0 (18.1-42.1) 90 1,045.9 8.6 (7.0-10.7)
Moderate 154 578.6 26.6 (22.5-31.7) 39 111.2 35.1 (25.8-48.9) 115 467.4 24.6 (20.2-30.1)
Severe 26 29.6 87.8 (57.0-138.2) 8 11.2 71.7 (36.0-159.2) 18 18.5 97.5 (57.1-171.8)
Updated CD4 cell count (cells/uL)          
≥500 67 1,763.1 3.8 (3.0-4.9) 0 1.8 0 67 1,761.1 3.8 (3.0-4.9)
200-499 200 3,055.9 6.5 (5.7-7.6) 5 47.8 10.5 (4.4-31.0) 195 3,008.1 6.5 (5.6-7.5)
100-199 104 827.2 12.6 (10.4-15.4) 29 132.1 21.9 (15.4-32.4) 75 695.1 10.8 (8.6-13.7)
<100 105 292.9 35.8 (29.6-43.8) 53 127.0 41.7 (32.0-55.3) 52 165.9 31.3 (23.9-41.6)
Total 476 5,939.1 8.0 (7.3-8.8) 87 308.8 28.2 (22.9-35.0) 389 5,630.0 6.9 (6.2-7.7)
  1. Abbreviations:ART antiretroviral therapy, CI confidence interval, TB tuberculosis; WHO World Health Organization.
  2. *Person-time accrued during treatment of prevalent or incident TB (520.1 PYs) was excluded when calculating TB incidence rates.