Table 3 Poisson regression of risk factors for incident TB among patients receiving ART

Age (for each year decrease)

1.01 (1.00-1.02)

0.091

1.01 (1.00-1.03)

0.018

Gender

Female

1.0

0.458

Male

1.08 (0.89-1.31)

WHO stage at baseline**

0.003

1/2

1.0

1.0

0.457

3/4

1.44 (1.12-1.84)

1.10 (0.85-1.44)

Baseline anaemia severity

None

1.0

0.067

Mild

0.96 (0.72-1.27)

Moderate

1.27 (0.99-1.62)

Severe

1.42 (0.87-2.32)

Baseline CD4 category (cells/μL)

≥150

1.0

0.298

100-149

1.25 (0.96-1.63)

50-99

1.21 (0.93-1.57)

<50

1.22 (0.94-1.58)

Baseline viral load (cells/mL)

<5.0

1.0

0.984

≥5.0

1.00 (0.96-1.04)

CD4 category (cells/μL) (updated)**

≥500

1.0

<0.001

1.0

<0.001

200-499

1.65 (1.25-2.18)

1.49 (1.11-1.99)

100-199

2.93 (2.16-3.99)

2.02 (1.41-2.89)

<100

6.63 (4.88-9.00)

3.15 (2.10-4.73)

Viral load (cells/mL) (updated)**

<1,000

1.0

<0.001

1.0

0.005

≥1,000

3.31 (2.74-4.00)

1.48 (1.13-1.94)

WHO anaemia severity (updated)**

None

1.0

<0.001

1.0

<0.001

Mild

2.15 (1.70-2.71)

1.98 (1.56-2.51)

Moderate

5.011 (4.13-6.33)

3.80 (3.00-4.80)

Severe

13.61 (9.02-20.52)

8.19 (5.29-12.69)

Duration of ART (months)

<4

1.0

<0.001

1.0

0.476

4-12

0.46 (0.34-0.63)

1.15 (0.81-1.63)

12-24

0.35 (0.26-0.47)

1.35 (0.94-1.93)

24-36

0.33 (0.24-0.45)

1.38 (0.95-2.01)

36-48

0.34 (0.25-0.46)

1.47 (1.01-2.14)

48-60

0.29 (0.20-0.40)

1.30 (0.86-1.95)

>60

0.26 (0.18-0.37)

1.16 (0.75-1.79)

Past history of TB

No

1.0

<0.001

1.0

<0.001

Yes

1.47 (1.23-1.77)

1.55 (1.28-1.89)

Prevalent TB

No

1.0

0.473

Yes

0.93 (0.75-1.14)

Recurrent TB

No

1.0

0.104

Yes

1.18 (0.96-1.46)