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Table 4 Association between the platelet count and clinical and other laboratory indices on admission

From: The clinical implications of thrombocytopenia in adults with severe falciparum malaria: a retrospective analysis

Variable Platelets ≥ 50 × 10 9 /L n = 319 Platelets <50 × 10 9 /L n = 328 P
Died 30/319 (9.4%) 77/328 (23.5%) <0.001
Age (years) 28 (22 to 38) 33 (24 to 45) <0.001
Sex (% male) 237/319 (74.0%) 246/327 (75.2%) 0.79
Temperature (°C) 38.5 (37.5 to 39.0) 38.1 (37.5 to 39.2) 0.74
Mean arterial pressure (mmHg) 76.7 (70.0 to 86.7) 78.3 (70.0 to 90.0) 0.05
Heart rate (beats/minute) 100 (96 to 120) 110 (95 to 120) 0.09
Respiratory rate (breaths/minute) 28 (24 to 32) 28 (24 to 36) 0.006
Glasgow Coma Scale Score 10 (8 to 15) 11 (8 to 15) 0.11
Haematocrit (%) 28 (23 to 35) 31 (25 to 38) <0.001
White cell count (× 109/L) 8.8 (6.3 to 11.6) 8.6 (6.1 to 12.6) 0.75
Reticulocyte count (%) 0.9 (0.5 to 1.5) 0.6 (0.3 to 1.0) <0.001
Parasite count (parasites/mL) 42.2 (10.4 to 184.3) 151.6 (32.3 to 479.9) <0.001
Sequestration (% blocked capillaries) 6.6 (1.7 to 18.3) 16.6 (6.6 to 34.9) 0.01
PfHRP2 (ng/mL) 1,739 (783 to 3,203) 2,834 (1,482 to 5,209) 0.01
Lactate (mmol/L) 2.9 (1.9 to 4.4) 4.0 (2.4 to 6.3) <0.001
Base deficit (mEq/L) 4 (1 to 8) 6 (3 to 11) <0.001
Creatinine (μmol/L) 164 (115 to 264) 185 (138 to 310) 0.007
Total bilirubin (μmol/L) 44.2 (23.8 to 115.6) 74.8 (40.8 to 170.0) <0.001
Indirect bilirubin (μmol/L) 26.5 (13.6 to 54.4) 47.6 (23.8 to 85.0) <0.001
Angiopoietin-2 (ng/mL) 16.3 (9.4 to 30.2) 19.4 (11.6 to 29.8) 0.14
Anuric on admission 20/289 (6.9%) 31/276 (11.2%) 0.07
Shock on admission 19/319 (6.0%) 28/328 (8.5%) 0.21
Pulmonary oedema on admission 6/319 (1.9%) 9/327 (2.8%) 0.46
  1. The values represented the median (interquartile range) and absolute number (%). PfHRP2: Plasmodium falciparum histidine rich protein 2.