Table 4 Association between the platelet count and clinical and other laboratory indices on admission
Variable | Platelets ≥ 50 × 10 9 /L n = 319 | Platelets <50 × 10 9 /L n = 328 | P |
|---|---|---|---|
Died | 30/319 (9.4%) | 77/328 (23.5%) | <0.001 |
Age (years) | 28 (22 to 38) | 33 (24 to 45) | <0.001 |
Sex (% male) | 237/319 (74.0%) | 246/327 (75.2%) | 0.79 |
Temperature (°C) | 38.5 (37.5 to 39.0) | 38.1 (37.5 to 39.2) | 0.74 |
Mean arterial pressure (mmHg) | 76.7 (70.0 to 86.7) | 78.3 (70.0 to 90.0) | 0.05 |
Heart rate (beats/minute) | 100 (96 to 120) | 110 (95 to 120) | 0.09 |
Respiratory rate (breaths/minute) | 28 (24 to 32) | 28 (24 to 36) | 0.006 |
Glasgow Coma Scale Score | 10 (8 to 15) | 11 (8 to 15) | 0.11 |
Haematocrit (%) | 28 (23 to 35) | 31 (25 to 38) | <0.001 |
White cell count (× 109/L) | 8.8 (6.3 to 11.6) | 8.6 (6.1 to 12.6) | 0.75 |
Reticulocyte count (%) | 0.9 (0.5 to 1.5) | 0.6 (0.3 to 1.0) | <0.001 |
Parasite count (parasites/mL) | 42.2 (10.4 to 184.3) | 151.6 (32.3 to 479.9) | <0.001 |
Sequestration (% blocked capillaries) | 6.6 (1.7 to 18.3) | 16.6 (6.6 to 34.9) | 0.01 |
PfHRP2 (ng/mL) | 1,739 (783 to 3,203) | 2,834 (1,482 to 5,209) | 0.01 |
Lactate (mmol/L) | 2.9 (1.9 to 4.4) | 4.0 (2.4 to 6.3) | <0.001 |
Base deficit (mEq/L) | 4 (1 to 8) | 6 (3 to 11) | <0.001 |
Creatinine (μmol/L) | 164 (115 to 264) | 185 (138 to 310) | 0.007 |
Total bilirubin (μmol/L) | 44.2 (23.8 to 115.6) | 74.8 (40.8 to 170.0) | <0.001 |
Indirect bilirubin (μmol/L) | 26.5 (13.6 to 54.4) | 47.6 (23.8 to 85.0) | <0.001 |
Angiopoietin-2 (ng/mL) | 16.3 (9.4 to 30.2) | 19.4 (11.6 to 29.8) | 0.14 |
Anuric on admission | 20/289 (6.9%) | 31/276 (11.2%) | 0.07 |
Shock on admission | 19/319 (6.0%) | 28/328 (8.5%) | 0.21 |
Pulmonary oedema on admission | 6/319 (1.9%) | 9/327 (2.8%) | 0.46 |