| |
Stroke
|
Cardiovascular events
|
Total mortality
|
|---|
|
Frailty index
|
HR
|
95% CI
|
HR
|
95% CI
|
HR
|
95% CI
|
|---|
|
0.1
|
0.75
|
0.40–1.38
|
0.62
|
0.42–0.92
|
0.89
|
0.63–1.25
|
|
0.2
|
0.66
|
0.43–1.01
|
0.60
|
0.45–0.78
|
0.84
|
0.66–1.07
|
|
0.3
|
0.59
|
0.36–0.96
|
0.57
|
0.42–0.79
|
0.80
|
0.61–1.04
|
|
0.4
|
0.52
|
0.25–1.09
|
0.55
|
0.34–0.89
|
0.76
|
0.50–1.14
|
|
0.5
|
0.47
|
0.16–1.33
|
0.53
|
0.26–1.06
|
0.72
|
0.40–1.29
|
|
0.6
|
0.41
|
0.10–1.65
|
0.50
|
0.20–1.27
|
0.68
|
0.32–1.48
|
- All models adjusted by age, sex, and interaction between treatment and frailty index, and stratified by region of recruitment.
