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Table 1 The characteristic data of 66 patients in DOC

From: Cerebral response to subject’s own name showed high prognostic value in traumatic vegetative state

Pats.

Diag.

Sex/age, y

Cause

Lesions (CT or MRI)

Mon. after insult

Left auditory cortex(mm 3 )

Right auditory cortex(mm 3 )

3 mon. diagnosis

6 mon. diagnosis

12 mon. diagnosis

Activation type

VS1

VS

M/47

TBI

Brain stem lesions

8

0

0

VS

VS

VS

No

VS2

VS

F/55

CVA

Right temporal lobe lesions

26

14,025 (165)

13,005 (153)

VS

VS

VS

High

VS3

VS

M/20

TBI

Left temporal lobe lesions

20

0

10,115 (119)

VS

VS

MCS

High

VS4

VS

M/3Y.2 M

Anoxic brain injury

Diffuse brain contusion

4

1,700 (20)

0

VS

VS

VS

Primary

VS5

VS

M/64

TBI

Bilateral frontal and left temporal lobe lesions

8

8,245 (97)

0

VS

MCS

MCS

High

VS6

VS

M/59

TBI

Bilateral fontal, left parietal, and temporal lobe lesions

1

0

15,725 (185)

EMCS

MCS

MCS

High

VS7

VS

M/73

CVA

Right cerebellum lesions

2

2,210 (26)

3,485 (41)

MCS

VS

VS

Primary

VS8

VS

F/3

Meningitis

5

0

4,250 (50)

VS

VS

Died

Primary

VS9

VS

M/47

Anoxic brain injury

2

2,125 (25)

0

MCS

EMCS

EMCS

Primary

VS10

VS

F/69

TBI

Bilateral frontal, parietal lobe, and left temporal lobe lesions

4

15,130 (178)

0

VS

VS

VS

High

VS11

VS

M/20

TBI

Diffuse brain lesion

24

12,325 (145)

0

MCS

MCS

MCS

High

VS12

VS

M/31

TBI

Brain stem, right temporal lobe, and left frontal lobe lesions

6

0

1,275 (15)

MCS

MCS

MCS

Primary

VS13

VS

M/48

TBI

Right frontal, temporal, parietal, and left frontal lobe lesions

2

30,515 (150)

6,375 (75)

MCS

Died

Died

High

VS14

VS

M/54

CVA

Right frontal and temporal lobe lesions

2

0

1,360 (16)

VS

VS

Died

Primary

VS15

VS

M/27

TBI

Diffuse brain contusion, subarachnoid hemorrhage

1

0

0

EMCS

EMCS

EMCS

No

VS16

VS

M/28

TBI

Diffuse brain hemorrhage

60

0

0

MCS

MCS

No

VS17

VS

M/17

Anoxic brain injury

Diffuse cortical atrophy

6

0

5,355 (63)

VS

VS

VS

High

VS18

VS

F/31

TBI

Right frontal and temporal lobe lesions

2

24,650 (290)

9,265 (109)

MCS

MCS

MCS

High

VS19

VS

F/8

TBI

Subdural fluid accumulation, cerebromalacia in right basal ganglia

3

0

23,630 (278)

MCS

MCS

MCS

High

VS20

VS

M/36

Anoxic brain injury

Diffuse brain contusion

2

0

2,550 (30)

VS

VS

VS

Primary

VS21

VS

M/24

Anoxic brain injury

Subarachnoid hemorrhage, diffuse brain contusion

2

1,360 (16)

2,380 (28)

VS

Primary

VS22

VS

M/60

TBI

Left parietal lobe hemorrhage

3

20,995 (247)

0

MCS

MCS

MCS

High

VS23

VS

M/19monh

TBI

Extensive brain lesions

2

9,010 (106)

40,885 (481)

MCS

MCS

MCS

High

VS24

VS

M/29

Anoxic brain injury

Diffuse cortical atrophy

48

1,360 (16)

0

VS

VS

VS

Primary

VS25

VS

M/42

TBI

Diffuse brain lesions

2

0

1,275 (15)

VS

VS

Primary

VS26

VS

F/52

TBI

Right frontal and left temporal lobe lesions

2

0

765 (9)

VS

VS

Primary

VS27

VS

M/38

TBI

Left occipital lobe and bilateral basal ganglia lesions

4

20,995 (247)

8,330 (98)

MCS

MCS

High

VS28

VS

M/21

TBI

Right temporal, frontal, and parietal lobe lesions

4

15,385 (180)

4,505 (53)

MCS

MCS

High

VS29

VS

M/58

Anoxic brain injury

Temporal and parietal lobe lesions

4

0

0

VS

VS

No

VS30

VS

M/61

TBI

Left temporal and frontal lobe lesions

8

0

0

VS

VS

Died

No

VS31

VS

M/63

TBI

Frontal and right temporal lobe contusion

18

0

2,530 (22)

VS

MCS

MCS

Primary

VS32

VS

F/45

TBI

Left subdural hematoma and extensive brain contusion

3

3,105 (27)

4,370 (38)

MCS

MCS

MCS

High

VS33

VS

M/45

TBI

Left epidural hematoma

12

3,450 (30)

0

VS

VS

VS

Primary

VS34

VS

M/23

Anoxic brain injury

Diffuse cortical atrophy

17

0

2,645 (23)

VS

VS

VS

Primary

VS35

VS

M/20

Anoxic brain injury

Diffuse cortical atrophy

7

0

0

VS

VS

VS

No

VS36

VS

M/43

CVA

Bilateral basal ganglia hemorrhage

3

19,090 (166)

8,970 (78)

VS

VS

VS

High

VS37

VS

M/21

TBI

Diffuse axonal injury, subarachnoid hemorrhage

6

3,680 (32)

0

VS

VS

VS

Primary

VS38

VS

F/38

Anoxic brain injury

Lateral ventricle expansion

3

0

0

VS

VS

VS

No

VS39

VS

M/54

Anoxic brain injury

Diffuse cortical atrophy

2

0

2,760 (24)

VS

VS

Primary

MCS1

MCS

F/46

TBI

Left temporal lobe lesions

3

0

11,645 (137)

MCS

EMCS

EMCS

High

MCS2

MCS

M/42

TBI

Bilateral frontal and left temporal lobe lesions

5

4,165 (49)

0

MCS

EMCS

EMCS

High

MCS3

MCS

M/45

TBI

Diffuse brain lesions

7

50,830 (598)

27,880 (328)

MCS

MCS

High

MCS4

MCS

M/46

TBI

Right frontal, temporal, and parietal lobe hematoma

4

12,580 (148)

5,100 (60)

VS

VS

VS

High

MCS5

MCS

M/33

TBI

Bilateral frontal and left parietal lobe lesions

1

12,750 (150)

0

EMCS

EMCS

EMCS

High

MCS6

MCS

F/29

TBI

Left frontal and parietal lobe hematoma

2

1,020 (12)

0

EMCS

EMCS

EMCS

Primary

MCS7

MCS

M/21

TBI

Left temporal hematoma and right subdural hematoma

3

9,095 (107)

28,390 (334)

MCS

MCS

Died

High

MCS8

MCS

M/65

TBI

Bilateral frontal lobe lesions, subarachnoid hemorrhage

3

0

19,550 (230)

EMCS

EMCS

EMCS

High

MCS9

MCS

M/20

TBI

Subarachnoid hemorrhage

3

23,120 (272)

12,240 (144)

MCS

MCS

MCS

High

MCS10

MCS

M/19

TBI

Diffuse axonal contusion

1

3,655 (43)

4,845 (57)

EMCS

EMCS

EMCS

High

MCS11

MCS

M/60

TBI

Left frontal and temporal hematoma

2

0

10,710 (126)

MCS

MCS

High

MCS12

MCS

M/32

TBI

Right frontal, bilateral temporal and parietal lobe lesions

2

935 (11)

1,445 (17)

EMCS

EMCS

EMCS

Primary

MCS13

MCS

F/64

CVA

Subarachnoid hemorrhage

8

7,140 (84)

0

EMCS

EMCS

EMCS

High

MCS14

MCS

M/30

TBI

Right temporal and frontal lobe lesions

2

23,120 (272)

16,405 (193)

MCS

EMCS

High

MCS15

MCS

F/24

TBI

Subdural hematoma, brainstem lesions

3

25,160 (296)

15,470 (179)

MCS

EMCS

High

MCS16

MCS

M/38

TBI

Bilateral temporal and frontal lobe lesions

6

0

22,780 (268)

MCS

MCS

High

MCS17

MCS

M/30

TBI

Left temporal and bilateral frontal lobe lesions

26

0

18,275 (215)

MCS

MCS

High

MCS18

MCS

M/50

CVA

Left basal ganglia and brain stem hemorrhage

14

0

805 (7)

MCS

MCS

MCS

Primary

MCS19

MCS

F/56

CVA

Brian stem hemorrhage

24

0

3,335 (29)

MCS

MCS

MCS

High

MCS20

MCS

F/59

CVA

Left basal ganglia and paraventricle hemorrhage

5

0

3,995 (47)

MCS

MCS

MCS

High

MCS21

MCS

M/62

CVA

Left cerebellum hemorrhage

17

1,035 (9)

0

MCS

MCS

MCS

Primary

MCS22

MCS

M/37

TBI

Bilateral frontal and left basal ganglia hemorrhage

4

0

2,760 (24)

EMCS

EMCS

EMCS

Primary

MCS23

MCS

M/42

TBI

Bilateral frontal and temporal contusion and hemorrhage

24

7,990 (94)

0

EMCS

EMCS

EMCS

High

MCS24

MCS

M/50

TBI

Brain stem, left temporal, right frontal and bilateral occipital contusion

9

8,925 (105)

0

MCS

MCS

MCS

High

MCS25

MCS

M/23

Anoxic brain injury

Diffuse axonal atrophy

28

0

11,845 (103)

MCS

MCS

MCS

High

EMCS1

EMCS

M/32

CVA

Bilateral basal ganglia, brain stem, and right cerebellum lesions

13

0

3,740 (44)

EMCS

EMCS

EMCS

Primary

EMCS2

EMCS

M/58

TBI

Left subdural hematoma

2

11,560 (136)

9,690 (114)

EMCS

EMCS

EMCS

High

  1. Show the characteristic data, activation volume (mm3) and voxel number (in brackets) of right and left side of auditory cortex, the follow-up diagnosis at 3, 6, and 12 months, and the activation type (Low, No, Lower level; High, higher level) of the patients with disorders of consciousness. TBI, Traumatic brain injury; CVA, Cerebrovascular accident; MCS, Minimally conscious state; EMCS, Emergence from minimally conscious state; VS, Vegetative state. Consent for the publication of the information relating to individual participants was obtained from the legal representative of all participants.