Pre-diagnostic concordance with the WCRF/AICR guidelines and survival in European colorectal cancer patients: a cohort study

Table 4 Hazard ratios (HR) and 95% confidence intervals (95% CIs) for CRC-related and overall mortality among CRC survivors associated with one standard deviation (SD) increment in the WCRF/AICR score after removing each component of the score at a time

	CRC-related mortality		Overall mortality
	HR ^a	95% CI	HR ^a	95% CI
WCRF/AICR score	0.90	(0.84–0.97)	0.93	(0.87–0.99)
WCRF/AICR score – Body fatness	0.93	(0.87–1.00)	0.96	(0.90–1.02)
WCRF/AICR score – Physical activity	0.92	(0.86–0.99)	0.94	(0.89–1.01)
WCRF/AICR score – Food promote weight gain	0.89	(0.83–0.96)	0.92	(0.87–0.98)
WCRF/AICR score – Plant foods	0.92	(0.85–0.99)	0.94	(0.89–1.01)
WCRF/AICR score – Animal foods	0.88	(0.82–0.94)	0.91	(0.86–0.97)
WCRF/AICR score – Alcohol	0.90	(0.84–0.96)	0.93	(0.87–0.99)
WCRF/AICR score – Breastfeeding^b	0.94	(0.85–1.04)	0.98	(0.88–1.08)

^aCox regression model, with age at CRC diagnosis as entry time and age at death or censoring as exit time, stratified by country and adjusted for year of CRC diagnosis, tumor stage, tumor grade, tumor site, sex, educational level, smoking status, plus the component that has been removed from the score. ^bIn women only.

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