Skip to main content

Table 1 Single nucleotide polymorphisms included in the genetic risk score in the RADIANT study

From: A genetic risk score combining 32 SNPs is associated with body mass index and improves obesity prediction in people with major depressive disorder

Chr Nearest gene SNP name Alleles BMI-increasing allele Frequency of BMI-increasing allele GWAS effect-size for BMI Call rate
1 NEGR1 rs2568958 A/G A 62.5% 0.13 99.95%
TNNI3K rs1514175 A/G A 42.3% 0.07 99.86%
PTBP2 rs11165643 C/T T 58.8% 0.06 99.07%
SEC16B rs10913469 C/T C 19.2% 0.22 100%
2 TMEM18 rs2867125 C/T C 82.9% 0.31 99.98%
ADCY3,RBJ rs10182181 A/G G 46.9% 0.14 99.40%
FANCL rs759250 A/G A 28.4% 0.1 100%
LRP1B rs6714473 C/T T 9.7% 0.09 99.85%
3 CADM2 rs7640855 A/G A 19.0% 0.1 96.83%
ETV5 rs7647305 C/T C 79.0% 0.14 99.93%
4 GNPDA2 rs12641981 C/T T 44.1% 0.18 100%
SLC39A8 rs13107325 C/T T 7.5% 0.19 99.91%
5 FLJ35779 rs253414 C/T T 66.4% 0.1 99.93%
ZNF608 rs6864049 A/G A 47.2% 0.07 100%
6 TFAP2B rs987237 A/G A 18.2% 0.13 100%
NUDT3 rs206936 A/G G 18.0% 0.06 95.99%
9 LRRN6C rs2183825 C/T C 32.9% 0.11 99.98%
11 STK33, RPL27A rs10840065 A/G A 51.6% 0.06 100%
BDNF rs6265 C/T C 79.8% 0.19 100%
MTCH2 rs10838738 A/G G 34.5% 0.06 100%
12 BCDIN3, FAIM2 rs7138803 A/G A 37.5% 0.12 100%
13 MTIF3 rs1475219 C/T C 20.4% 0.09 90.61%
14 PRKD1 rs11847697 C/T T 3.6% 0.17 96.87%
NRXN3 rs10146997 A/G G 21.9% 0.13 100%
15 MAP2K5 rs2241423 A/G G 77.2% 0.13 99.96%
16 GPRC5B rs12446632 A/G G 86.1% 0.17 99.93%
SH2B1 rs4788102 A/G A 39.0% 0.15 100%
FTO rs3751812 G/T T 41.0% 0.39 100%
18 MC4R rs921971 C/T C 26.6% 0.23 99.98%
19 KCTD15 rs29941 A/G G 68.3% 0.06 100%
ZC3H4, TMEM160 rs2303108 C/T C 71.4% 0.09 100%
QPCTL rs11083779 C/T T 95.8% 0.15 98.28%