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Table 1 Single nucleotide polymorphisms included in the genetic risk score in the RADIANT study

From: A genetic risk score combining 32 SNPs is associated with body mass index and improves obesity prediction in people with major depressive disorder

Chr

Nearest gene

SNP name

Alleles

BMI-increasing allele

Frequency of BMI-increasing allele

GWAS effect-size for BMI

Call rate

1

NEGR1

rs2568958

A/G

A

62.5%

0.13

99.95%

TNNI3K

rs1514175

A/G

A

42.3%

0.07

99.86%

PTBP2

rs11165643

C/T

T

58.8%

0.06

99.07%

SEC16B

rs10913469

C/T

C

19.2%

0.22

100%

2

TMEM18

rs2867125

C/T

C

82.9%

0.31

99.98%

ADCY3,RBJ

rs10182181

A/G

G

46.9%

0.14

99.40%

FANCL

rs759250

A/G

A

28.4%

0.1

100%

LRP1B

rs6714473

C/T

T

9.7%

0.09

99.85%

3

CADM2

rs7640855

A/G

A

19.0%

0.1

96.83%

ETV5

rs7647305

C/T

C

79.0%

0.14

99.93%

4

GNPDA2

rs12641981

C/T

T

44.1%

0.18

100%

SLC39A8

rs13107325

C/T

T

7.5%

0.19

99.91%

5

FLJ35779

rs253414

C/T

T

66.4%

0.1

99.93%

ZNF608

rs6864049

A/G

A

47.2%

0.07

100%

6

TFAP2B

rs987237

A/G

A

18.2%

0.13

100%

NUDT3

rs206936

A/G

G

18.0%

0.06

95.99%

9

LRRN6C

rs2183825

C/T

C

32.9%

0.11

99.98%

11

STK33, RPL27A

rs10840065

A/G

A

51.6%

0.06

100%

BDNF

rs6265

C/T

C

79.8%

0.19

100%

MTCH2

rs10838738

A/G

G

34.5%

0.06

100%

12

BCDIN3, FAIM2

rs7138803

A/G

A

37.5%

0.12

100%

13

MTIF3

rs1475219

C/T

C

20.4%

0.09

90.61%

14

PRKD1

rs11847697

C/T

T

3.6%

0.17

96.87%

NRXN3

rs10146997

A/G

G

21.9%

0.13

100%

15

MAP2K5

rs2241423

A/G

G

77.2%

0.13

99.96%

16

GPRC5B

rs12446632

A/G

G

86.1%

0.17

99.93%

SH2B1

rs4788102

A/G

A

39.0%

0.15

100%

FTO

rs3751812

G/T

T

41.0%

0.39

100%

18

MC4R

rs921971

C/T

C

26.6%

0.23

99.98%

19

KCTD15

rs29941

A/G

G

68.3%

0.06

100%

ZC3H4, TMEM160

rs2303108

C/T

C

71.4%

0.09

100%

QPCTL

rs11083779

C/T

T

95.8%

0.15

98.28%