Table 4 Antibiotic exposure by randomization group with subgroup analysis

All patients (intention-to-treat)

(n = 64)

(n = 61)

 Duration of initial antibiotic therapy

10.0 (7.0–11.0)

6.0 (4.0–8.0)

 Antibiotic exposure within 90 days

10.0 (7.0–16.0)

7.0 (5.0–14.0)

Per-protocol population

(n = 52)

(n = 44)

 Duration of initial antibiotic therapy

10.0 (7.0–11.0)

6.0 (4.0–7.0)

 Antibiotic exposure within 90 days

10.0 (7.5–16.0)

7.0 (5.0–14.5)

Female patients

(n = 52)

(n = 43)

 Duration of initial antibiotic therapy

9.0 (7.0–10.5)

5.0 (4.0–7.0)

 Antibiotic exposure within 90 days

10.0 (7.0–14.0)

7.0 (4.0–13.0)

Male patients

(n = 12)

(n = 18)

 Duration of initial antibiotic therapy

11.0 (10.5–12.0)

6.5 (5.0–9.0)

 Antibiotic exposure within 90 days

16.0 (11.0–21.0)

9.0 (6.0–19.0)

Inpatients

(n = 45)

(n = 45)

 Duration of initial antibiotic therapy

10.0 (8.0–11.0)

7.0 (5.0–9.0)

 Antibiotic exposure within 90 days

11.0 (10.0–18.5)

8.5 (6.5–16.5)

Uncomplicated simple UTI

(n = 6)

(n = 2)

 Duration of initial antibiotic therapy

1.0 (1.0–1.0)

0.5 (0.0–1.0)

 Antibiotic exposure within 90 days

1.0 (1.0–1.0)

4.0 (1.0–7.0)

Complicated simple UTI

(n = 12)

(n = 16)

 Duration of initial antibiotic therapy

7.0 (7.0–9.0)

4.0 (2.5–5.5)

 Antibiotic exposure within 90 days

10.0 (8.0–12.0)

5.5 (3.0–14.0)

Uncomplicated febrile UTI/pyelonephritis

(n = 8)

(n = 9)

 Duration of initial antibiotic therapy

7.0 (7.0–7.5)

4.0 (4.0–6.0)

 Antibiotic exposure within 90 days

7.0 (7.0–10.5)

6.5 (4.0–11.0)

Complicated febrile UTI/pyelonephritis

(n = 34)

(n = 33)

 Duration of initial antibiotic therapy

10.5 (10.0–11.0)

7.0 (6.0–9.0)

 Antibiotic exposure within 90 days

11.0 (10.0–18.0)

7.5 (6.5–13.5)