Skip to main content

Advertisement

Table 5 Rates of adverse outcomes

From: Procalcitonin and pyuria-based algorithm reduces antibiotic use in urinary tract infections: a randomized controlled trial

  Control group PCT/Pyuria group Odds ratio 95% CI P value a
All patients (intention-to-treat) (n = 64) (n = 61)    
 Recurrence 14/63 (22%) 15/59 (25%) 1.19 0.52–2.75 0.68
 Rehospitalization 17/63 (27%) 15/59 (25%) 0.92 0.41–2.07 0.85
 Death 4/63 (6%) 1/59 (2%) 0.25 0.03–2.30 0.22
Per-protocol population (n = 52) (n = 44)    
 Recurrence 11/52 (21%) 14/44 (32%) 1.74 0.69–4.36 0.24
 Rehospitalization 13/52 (35%) 13/44 (41%) 1.26 0.51–3.10 0.62
 Death 1/52 (2%) 0    
Inpatients (n = 45) (n = 45)    
 Recurrence 11 (25%) 13 (30%) 1.26 0.49–3.22 0.63
 Rehospitalization 15 (34%) 13 (30%) 0.81 0.28–0.96 0.65
Uncomplicated simple UTI (n = 6) (n = 2)    
 Recurrence 1/6 (17%) 1/2 (50%) 5.00 0.15–166.59 0.37
 Rehospitalization 1/6 (17%) 1/2 (50%) 5.00 0.15–166.59 0.37
Complicated simple UTI (n = 12) (n = 16)    
 Recurrence 3/11 (27%) 6/16 (38%) 1.60 0.30–8.49 0.58
 Rehospitalization 2/11 (18%) 6/16 (38%) 2.70 0.43–16.94 0.29
Uncomplicated febrile UTI/pyelonephritis (n = 8) (n = 9)    
 Recurrence 1/8 (13%) 2/8 (25%) 2.33 0.17–32.58 0.53
 Rehospitalization 2/8 (25%) 1/8 (13%) 0.43 0.03–5.98 0.53
Complicated febrile UTI/pyelonephritis (n = 34) (n = 33)    
 Recurrence 8/34 (24%) 6/32 (19%) 0.75 0.23–2.47 0.64
 Rehospitalization 11/34 (32%) 7/32 (22%) 0.59 0.19–1.77 0.34
  1. aLogistic regression analysis.