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Table 1 Comparison of the plasma phospholipid fatty acid changes for treatments that exclusively increase ALA (Jones et al. [8]) vs. those that decrease LA and increase ALA (Hsieh et al. [9])

From: Balancing omega-6 and omega-3 fatty acids in ready-to-use therapeutic foods (RUTF)

 

Intake (% wt)

 

Plasma phospholipid DHA (% wt)

Jones et al. [8], BMC Medicine 2015

 

n = 20 per group

 

LA

ALA

Basal

28 d

Diff (%)

 

Control

S-RUTF

14.9

1.3

2.51

2.23

−11%

n.s.

 

F-RUTF

14.4

6.2

2.63

2.08

−21%

n.s.

Hsieh et al. [9], JPGN 2015

 

Control, n = 38; HO-RUTF, n = 43

 

Control

C-RUTF

21.3

0.4

3.24

2.43

−25%

P = 0.04

 

HO-RUTF

13.1

13.1

2.84

2.96

4%

n.s.

  1. Jones et al. [8]: From entry DHA drops non-significantly from baseline with a 4.7-fold increase in ALA from flax with no change in LA for both standard (S) and flax oil supplemented (F) RUTF. Hsieh et al. [9]: DHA drops dramatically in control (C); the drop in LA in high oleic (HO) prevents the decrease. Units are percent by weight of fatty acids.
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BMC Medicine

ISSN: 1741-7015

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