Skip to main content

Table 1 Clinical data

From: Severe malaria in children leads to a significant impairment of transitory otoacoustic emissions - a prospective multicenter cohort study

 

Parameter units

Severe malaria

Cerebral malaria

p-value

  

Result

Mean (SD)

Result

Mean (SD)

Severe malaria vs cerebral malaria

Parasitemia

Parasites/μl

114

97,111 (1,271,985)

24

139,743 (683,264)

NSd

Pulse

/min

120

126 (22)

24

132 (21)

NSc

Temperature

Celsius

120

38.3 (1.24)

24

37.9 (1.17)

NSc

Respiratory rate

/min

120

37.1 (11.5)

24

42.9 (12.3)

0.027c

Hemoglobin

g/dl

119

8.7 (2.3)

24

8.3 (2.7)

NSc

Platelets

1000/ μl

119

109.310 (94.924)

24

67.458 (50.113)

0.016d

White blood cells

1000 /μl

119

9.7 (6.7)

24

10.2 (4.1)

NSd

Glucose

mmol/l

98

5.169 (2.342)

20

4.895 (2.521)

NSc

Creatinine

g/l

96

23.5 (91)b

18

31.5 (568)b

NSd

Bilirubin

g/l

99

27.5 (184)b

21

29 (77)b

NSd

ALT

U/l

101

32.2 (33.4)

20

34.9 (26.9)

NSd

Hemoglobinuria

% of included patients

119

1.7 %

24

4.2 %

NSe

Respiratory distress

% of included patients

119

4.2 %

24

12.5 %

NSf

Deep breathing

% of included patients

120

1.7 %

24

0 %

NSf

Severe vomiting

% of included patients

119

2.5 %

24

4.2 %

NSf

Prostration

% of included patients

119

16.8 %

24

54.2 %

0.000f

Coma

% of included patients

119

0 %

24

37.5 %

0.000f

Repeated generalized seizures

% of included patients

119

0 %

24

50 %

0.000f

Jaundice

% of included patients

119

4.2 %

24

12.5 %

NSf

Severe anemia

% of included patients

119

10.1 %

24

20.8 %

NSe

Hypoglycemia

% of included patients

119

2.5 %

24

8.3 %

0.03e

  1. The results of the evaluated clinical data are listed for patients with severe malaria and with cerebral malaria
  2. Mean and standard deviation are given for continuous variables; comparison between groups has been performed by the indicated tests. NS, not significant
  3. aGeometric mean (range); bmedian (range); cStudents t-test; dMann–Whitney U test; echi-square test; fFisher’s exact test