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Table 1 Clinical data

From: Severe malaria in children leads to a significant impairment of transitory otoacoustic emissions - a prospective multicenter cohort study

  Parameter units Severe malaria Cerebral malaria p-value
   Result Mean (SD) Result Mean (SD) Severe malaria vs cerebral malaria
Parasitemia Parasites/μl 114 97,111 (1,271,985) 24 139,743 (683,264) NSd
Pulse /min 120 126 (22) 24 132 (21) NSc
Temperature Celsius 120 38.3 (1.24) 24 37.9 (1.17) NSc
Respiratory rate /min 120 37.1 (11.5) 24 42.9 (12.3) 0.027c
Hemoglobin g/dl 119 8.7 (2.3) 24 8.3 (2.7) NSc
Platelets 1000/ μl 119 109.310 (94.924) 24 67.458 (50.113) 0.016d
White blood cells 1000 /μl 119 9.7 (6.7) 24 10.2 (4.1) NSd
Glucose mmol/l 98 5.169 (2.342) 20 4.895 (2.521) NSc
Creatinine g/l 96 23.5 (91)b 18 31.5 (568)b NSd
Bilirubin g/l 99 27.5 (184)b 21 29 (77)b NSd
ALT U/l 101 32.2 (33.4) 20 34.9 (26.9) NSd
Hemoglobinuria % of included patients 119 1.7 % 24 4.2 % NSe
Respiratory distress % of included patients 119 4.2 % 24 12.5 % NSf
Deep breathing % of included patients 120 1.7 % 24 0 % NSf
Severe vomiting % of included patients 119 2.5 % 24 4.2 % NSf
Prostration % of included patients 119 16.8 % 24 54.2 % 0.000f
Coma % of included patients 119 0 % 24 37.5 % 0.000f
Repeated generalized seizures % of included patients 119 0 % 24 50 % 0.000f
Jaundice % of included patients 119 4.2 % 24 12.5 % NSf
Severe anemia % of included patients 119 10.1 % 24 20.8 % NSe
Hypoglycemia % of included patients 119 2.5 % 24 8.3 % 0.03e
  1. The results of the evaluated clinical data are listed for patients with severe malaria and with cerebral malaria
  2. Mean and standard deviation are given for continuous variables; comparison between groups has been performed by the indicated tests. NS, not significant
  3. aGeometric mean (range); bmedian (range); cStudents t-test; dMann–Whitney U test; echi-square test; fFisher’s exact test