Table 2 Severe acute respiratory distress syndrome (ARDS) patients’ baseline characteristics with regard to statin usage

Age, years

61 ± 14

59 ± 15

67 ± 10

0.0159

Male, %

66

64

73

0.4822

Body mass index

30 ± 8

30 ± 9

30 ± 6

0.5590

Severity of sepsis

Sepsis/severe sepsis, %

24

19

39

0.0644

 Septic shock, %

76

81

62

0.0644

 Sequential Organ Failure Assessment score

11.0 ± 3.5

11.2 ± 3.5

10.6 ± 3.4

0.2511

Acute Physiology and Chronic Health Evaluation (APACHE II) score

23.7 ± 6.7

23.4 ± 6.9

24.5 ± 5.7

0.3250

Comorbidities, %

 Hypertension

58

51

81

0.0073

 History of myocardial infarction

4

2

12

0.0772

 Chronic obstructive pulmonary disease

18

19

15

0.7787

 Renal dysfunction

10

9

12

0.7114

 Noninsulin-dependent diabetes mellitus

9

7

15

0.2323

 Insulin-dependent diabetes mellitus

12

13

12

1.0000

 Chronic liver disease

4

2

12

0.0772

 History of cancer

19

22

12

0.3964

 History of stroke

6

2

19

0.0066

Recent surgical history, %

 Elective surgery

25

19

42

0.0217

 Emergency surgery

46

49

35

0.2635

 No history of surgery

30

32

23

0.4704

Site of infection, %

0.5675

 Lung

71

68

81

 Abdomen

11

13

4

 Bone or soft tissue

7

8

4

 Surgical wound

1

1

0

 Urogenital

1

1

0

 Primary bacteremia

7

6

12

 Other

3

3

0

Organ support, %

 Mechanical ventilation

96

96

96

1.0000

 Use of vasopressor

76

81

62

0.0644

 Renal replacement therapy

11

10

12

1.0000

Statin drugs, %

 Simvastatin

20

96

 Pravastatin

1

4