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Table 2 Patient characteristics

From: Comparative efficacy of serotonin (5-HT3) receptor antagonists in patients undergoing surgery: a systematic review and network meta-analysis

Total no. of patients

80,410

 

Mean, Median sample size

181, 118

 

Mean % female

72

 
 

No. of studies (n = 444) *

Percentage of studies

Age category

  

Children only (aged <18 yr)

75

16.89

Adults only (aged ≥18 yr to ≤65 yr)

262

59.01

Children and adults (aged ≤65 yr)

17

3.83

Adults and elderly (aged ≥18 yr)

76

17.12

All ages

9

2.03

Not reported

5

1.13

American Society of Anesthesiologists (ASA) physical status

  

I

15

3.38

I or II

266

59.91

I or II or III

87

19.59

II or III

4

0.90

Not reported

72

16.22

Surgery type

  

Obstetric and gynecological

134

30.18

Gastrointestinal

51

11.49

Eye

35

7.88

General dentistry, oral and maxillofacial surgery, and orthodontics

35

7.88

Otolaryngological

20

4.50

Breast

18

4.05

Orthopedic

16

3.60

Neurological

15

3.38

Endocrine

9

2.03

Cardiovascular

3

0.68

Urological

1

0.23

Miscellaneous (includes multiple surgery types, abdominal surgery, and plastic surgery unspecified)

103

23.20

Not reported

4

0.90

History of motion sickness

  

Yes

147

33.11

No or not reported

297

66.89

History of postoperative nausea and vomiting

  

Yes

197

44.37

No or not reported

247

55.63

Comorbidities **

  

Not reported

415

93.47

Diabetes mellitus

9

2.03

Cardiovascular

8

1.80

Obesity

5

1.13

Cancer

4

0.90

Migraines

3

0.68

Gallbladder

2

0.45

Liver disease

2

0.45

Asthma

1

0.23

Disorder of the ear

1

0.23

Mental health

1

0.23

Osteoarthritis

1

0.23

Urological

1

0.23

  1. * Includes unpublished data; ** Some studies considered more than one comorbidity