Table 1 Baseline characteristics of the original and the extended cohort of the Rotterdam Study
RS-I | RS-II | P value for difference | |
|---|---|---|---|
N = 7,003 | N = 2,953 | ||
Age, years | 69.4 (9.1) | 65.0 (8.3) | <0.001 |
Sex, female | 4187 (59.8 %) | 1661 (56.2 %) | 0.15 |
Body mass index | |||
<18.5 | 69 (1.0 %) | 15 (0.6 %) | 0.65 |
18.5–25 | 2486 (37.5 %) | 790 (29.9 %) | Reference |
25–30 | 3097 (46.7 %) | 1286 (48.6 %) | <0.001 |
>30 | 977 (14.7 %) | 555 (21.0 %) | <0.001 |
Hypertension | 3793 (56.3 %) | 1688 (61.9 %) | <0.001 |
Diabetes mellitus | 727 (10.5 %) | 319 (10.9 %) | 0.001 |
Total cholesterol, mmol/L | 6.6 (1.2) | 5.8 (1.0) | <0.001 |
HDL cholesterol, mmol/L | 1.3 (0.4) | 1.4 (0.4) | 0.004 |
Lipid lowering medication | 164 (2.3 %) | 367 (12.5 %) | <0.001 |
Smoking | |||
Former | 2848 (41.7 %) | 1381 (47.4 %) | 0.001 |
Current | 1560 (22.8 %) | 678 (23.3 %) | 0.60 |
Educational level | |||
Intermediate | 2540 (37.3 %) | 1429 (49.4 %) | <0.001 |
Low | 3700 (54.3 %) | 975 (33.7 %) | <0.001 |
Stroke | 175 (2.5 %) | 94 (3.2 %) | <0.001 |
Coronary heart disease | 535 (8.4 %) | 163 (6.1 %) | 0.04 |
Heart failure | 220 (3.3 %) | 31 (1.2 %) | 0.01 |
Atrial fibrillation | 316 (4.9 %) | 79 (3.6 %) | 0.44 |