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Table 2 Patient characteristics

From: Comparative safety of serotonin (5-HT3) receptor antagonists in patients undergoing surgery: a systematic review and network meta-analysis

Total number of patients

27,787

 

Mean sample size

242

 

Mean percentage female (%)

64

 
 

Number of studies (n = 115)a

Percentage of studies (%)

Age category

  

Children only (aged <18 years)

22

19.1

Adults only (aged ≥18 years to ≤65 years)

72

62.6

Children and adults (aged ≤65 years)

2

1.7

Adults and elderly (aged ≥18 years)

16

13.9

All ages

2

1.7

Not reported

1

0.9

American Society of Anesthesiologists (ASA) physical status

  

I

4

3.5

I or II

62

53.9

I or II or III

32

27.8

Not reported

17

14.8

Surgery type

  

Obstetric and gynecological

37

32.2

Eye

12

10.4

Gastrointestinal

9

7.8

General dentistry, oral and maxillofacial surgery, and orthodontics

5

4.3

Orthopedic

5

4.3

Neurological

3

2.6

Otolaryngological

2

1.7

Breast

1

0.9

Cardiovascular

1

0.9

Urological

1

0.9

Miscellaneous (includes multiple surgery types, abdominal surgery, and plastic surgery unspecified)

39

33.9

History of motion sickness

  

Yes

49

42.6

No or not reported

66

57.4

History of postoperative nausea and vomiting

  

Yes

67

58.3

No or not reported

48

41.7

Comorbidities b

  

Not reported

109

94.8

Diabetes mellitus

3

2.6

Cardiovascular

2

1.7

Obesity

1

0.9

Urological

1

0.9

Migraines

1

0.9

Liver disease

1

0.9

  1. aIncludes unpublished data; bsome studies considered more than one comorbidity