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Table 2 Patient characteristics

From: Comparative safety of serotonin (5-HT3) receptor antagonists in patients undergoing surgery: a systematic review and network meta-analysis

Total number of patients 27,787  
Mean sample size 242  
Mean percentage female (%) 64  
  Number of studies (n = 115)a Percentage of studies (%)
Age category   
Children only (aged <18 years) 22 19.1
Adults only (aged ≥18 years to ≤65 years) 72 62.6
Children and adults (aged ≤65 years) 2 1.7
Adults and elderly (aged ≥18 years) 16 13.9
All ages 2 1.7
Not reported 1 0.9
American Society of Anesthesiologists (ASA) physical status   
I 4 3.5
I or II 62 53.9
I or II or III 32 27.8
Not reported 17 14.8
Surgery type   
Obstetric and gynecological 37 32.2
Eye 12 10.4
Gastrointestinal 9 7.8
General dentistry, oral and maxillofacial surgery, and orthodontics 5 4.3
Orthopedic 5 4.3
Neurological 3 2.6
Otolaryngological 2 1.7
Breast 1 0.9
Cardiovascular 1 0.9
Urological 1 0.9
Miscellaneous (includes multiple surgery types, abdominal surgery, and plastic surgery unspecified) 39 33.9
History of motion sickness   
Yes 49 42.6
No or not reported 66 57.4
History of postoperative nausea and vomiting   
Yes 67 58.3
No or not reported 48 41.7
Comorbidities b   
Not reported 109 94.8
Diabetes mellitus 3 2.6
Cardiovascular 2 1.7
Obesity 1 0.9
Urological 1 0.9
Migraines 1 0.9
Liver disease 1 0.9
  1. aIncludes unpublished data; bsome studies considered more than one comorbidity