Skip to main content

Table 7 Comparing rates of tuberculosis in 216,545 patients with type 2 diabetes (T2DM) by time-dependent treatment group with a matched unexposed cohort

From: Risk of tuberculosis in patients with diabetes: population based cohort study using the UK Clinical Practice Research Datalink

   

Crude

 

Fully adjusted modela

 

Exposure group

Number of patients

TB cases/PYb

Ratec (95 % CI)

Rate ratio

Rate ratio

P-value*

(% of T2DM)

(95 % CI)

(95 % CI)

Patients without diabetes

1,186,932

765/55.87

13.69 (12.76–14.70)

1.00

1.00

 

Patients with T2DM:

      

Without insulin exposure

190,865 (88.1)

161/10.05

16.02 (13.72–18.69)

1.16 (0.98–1.37)

1.27 (0.98–1.66)

0.119

During insulin exposure

25,680 (11.9)

28/1.33

21.07 (14.55–30.51)

1.63 (1.12–2.38)

1.49 (0.83–2.67)

 
  1. *P-value from likelihood ratio test
  2. aModel adjusted for: age, BMI, smoking status, alcohol status, ethnicity and IMD
  3. bPY: 100,000 person years at risk
  4. c Rate: per 100,000 person years
  5. BMI body mass index, CI confidence interval, IMD index of multiple deprivation, TB tuberculosis
Back to article page

BMC Medicine

ISSN: 1741-7015

Contact us