Skip to main content

Table 3 Quantitative measures of blood index

From: Intracoronary infusion of Wharton’s jelly-derived mesenchymal stem cells in acute myocardial infarction: double-blind, randomized controlled trial

Blood index Placebo WJMSCs P value
  (number = 55) (number = 57)
CD3(%)    
 Baseline 66.8±0.9 67.6±0.8 0.48
 3 Days 67.6±1.1 69.1±0.9 0.29
 P value(baseline vs.3d) 0.43 0.08  
 1 Mo 67.3±1.0 66.6±0.9 0.53
 P value (baseline vs.1 mo) 0.58 0.18  
 4 Mo 65.2±0.7 66.3±0.9 0.34
 P value (baseline vs.6 mo) 0.06 0.11  
 12 Mo 66.2±0.9 66.4±0.8 0.81
 P value (baseline vs.12 mo) 0.64 0.16  
 18 Mo 67.1±1.0 66.8±0.9 0.76
 P value (baseline vs.18 mo) 0.66 0.29  
CD4(%)    
 Baseline 39.6±1.2 40.1±0.8 0.70
 3 Days 40.4±1.1 39.3±0.8 0.39
 P value (baseline vs.3 d) 0.37 0.24  
 1 Mo 38.2±1.0 37.1±0.7 0.34
 P value (baseline vs.1 mo) 0.09 <0.0001  
 4 Mo 37.7±1.1 38.0±0.8 0.75
 P value (baseline vs.6 mo) 0.09 0.02  
 12 Mo 37.6±0.9 38.2±0.6 0.58
 P value (baseline vs.12 mo) 0.11 0.03  
 18 Mo 38.8±1.1 39.2±0.9 0.45
 P value (baseline vs.18 mo) 0.09 0.16  
CD8(%)    
 Baseline 21.9±0.9 22.4±0.8 0.39
 3 Days 21.3±0.8 22.9±0.8 0.13
 P value (baseline vs.3 d) 0.36 0.16  
 1 Mo 21.5±0.5 22.8±0.7 0.14
 P value (baseline vs.1 mo) 0.63 0.47  
 4 Mo 21.5±0.7 21.8±0.7 0.78
 P value (baseline vs.6 mo) 0.66 0.32  
 12 Mo 23.2±0.4 22.2±0.6 0.16
 P value (baseline vs.12 mo) 0.12 0.80  
 18 Mo 22.4±0.7 23.6±0.9 0.21
 P value (baseline vs.18 mo) 0.56 0.71  
IgG(g/L)    
 Baseline 11.1±0.3 10.7±0.3 0.42
 3 Days 11.3±0.3 11.0±0.2 0.34
 P value (baseline vs.3d) 0.41 0.39  
 1 Mo 11.5±0.4 10.9±0.4 0.13
 P value (baseline vs.1 mo) 0.10 0.63  
 4 Mo 10.9±0.4 10.3±0.4 0.48
 P value (baseline vs.6 mo) 0.74 0.36  
 12 Mo 11.8±0.3 11.3±0.4 0.31
 P value (baseline vs.12 mo) 0.09 0.13  
 18 Mo 11.6±0.5 11.1±0.5 0.18
 P value (baseline vs.18 mo) 0.11 0.64  
IgM(g/L)    
 Baseline 1.10±0.10 1.07±0.08 0.80
 3 Days 1.15±0.09 1.05±0.07 0.38
 P value (baseline vs.3d) 0.24 0.67  
 1 Mo 1.24±0.11 1.23±0.10 0.69
 P value (baseline vs.1 mo) 0.28 0.15  
 4 Mo 1.17±0.10 1.05±0.08 0.35
 P value (baseline vs.6 mo) 0.50 0.69  
 12 Mo 1.14±0.06 1.15±0.05 0.55
 P value (baseline vs.12 mo) 0.66 0.19  
 18 Mo 1.35±0.11 1.31±0.10 0.59
 P value (baseline vs.18 mo) 0.39 0.24  
CEA(ng/ml)    
 Baseline 2.21±0.14 2.63±0.17 0.08
 3 Days 2.47±0.15 2.55±0.17 0.71
 P value (baseline vs.3 d) 0.03 0.48  
 1 Mo 2.33±0.14 2.76±0.19 0.11
 P value (baseline vs.1 mo) 0.33 0.40  
 4 Mo 2.37±0.15 2.42±0.15 0.91
 P value (baseline vs.6 mo) 0.25 0.21  
 12 Mo 2.33±0.18 2.44±0.16 0.62
 P value (baseline vs.12 mo) 0.58 0.34  
 18 Mo 2.22±0.16 2.55±0.24 0.16
 P value (baseline vs.18 mo) 0.21 0.34  
CRP(mg/L)    
 Baseline 5.72±0.53 6.47±0.49 0.27
 3 Days 4.99±0.51 5.47±0.48 0.31
 P value (baseline vs.3 d) 0.12 0.06  
 1 Mo 3.70±0.40 3.54±0.31 0.80
 P value (baseline vs.1 mo) <0.0001 <0.0001  
 4 Mo 3.20±0.33 3.34±0.30 0.54
 P value (baseline vs.6 mo) <0.0001 <0.0001  
 12 Mo 3.04±0.19 3.00±0.29 0.46
 P value (baseline vs.12 mo) <0.0001 <0.0001  
 18 Mo 3.56±0.43 3.42±0.38 0.76
 P value (baseline vs.18 mo) <0.0001 <0.0001  
ALT(U/L)    
 Baseline 30.5±1.8 32.8±2.1 0.41
 3 Days 31.6±2.1 32.9±2.7 0.85
 P value (baseline vs.3 d) 0.42 0.98  
 1 Mo 30.3±1.8 28.3±1.3 0.68
 P value (baseline vs.1 mo) 0.96 0.47  
 4 Mo 29.3±1.1 29.9±1.2 0.72
 P value (baseline vs.6 mo) 0.87 0.59  
 12 Mo 27.2±1.1 27.4±1.1 0.94
 P value (baseline vs.12 mo) 0.36 0.31  
 18 Mo 29.2±1.4 28.1±1.2 0.61
 P value (baseline vs.18 mo) 0.83 0.43  
TBIL(μmol/L)    
 Baseline 16.7±1.5 15.1±1.3 0.63
 3 Days 11.6±0.6 11.5±0.5 0.89
 P value (baseline vs.3 d) 0.0003 0.006  
 1 Mo 15.1±0.7 13.8±0.6 0.32
 P value (baseline vs.1 mo) 0.32 0.31  
 4 Mo 14.5±1.0 16.0±1.1 0.27
 P value (baseline vs.6 mo) 0.22 0.60  
 12 Mo 14.2±0.7 15.6±0.5 0.12
 P value (baseline vs.12 mo) 0.14 0.76  
 18 Mo 14.6±0.7 13.4±0.6 0.36
 P value (baseline vs.18 mo) 0.31 0.28  
BUN(mmol/L)    
 Baseline 5.30±0.18 5.63±0.22 0.28
 3 Days 4.91±0.19 5.19±0.17 0.12
 P value (baseline vs.3 d) 0.06 0.07  
 1 Mo 5.10±0.18 5.26±0.23 0.96
 P value (baseline vs.1 mo) 0.36 0.22  
 4 Mo 5.29±0.17 5.21±0.18 0.47
 P value (baseline vs.6 mo) 0.95 0.13  
 12 Mo 5.42±0.18 5.46±0.20 0.89
 P value (baseline vs.12 mo) 0.68 0.57  
 18 Mo 5.22±0.23 5.33±0.32 0.85
 P value (baseline vs.18 mo) 0.46 0.29  
CRE(μmol/L)    
 Baseline 84.5±2.3 81.8±2.2 0.39
 3 Days 81.2±2.0 77.9±2.1 0.26
 P value (baseline vs.3 d) 0.14 0.14  
 1 Mo 78.5±2.4 76.3±2.0 0.46
 P value (baseline vs.1 mo) 0.06 0.07  
 4 Mo 83.5±2.2 78.2±2.0 0.07
 P value (baseline vs.6 mo) 0.71 0.17  
 12 Mo 84.0±2.0 80.4±1.8 0.19
 P value (baseline vs.12 mo) 0.84 0.63  
 18 Mo 82.6±2.1 79.7±2.7 0.48
 P value (baseline vs.18 mo) 0.56 0.61  
  1. Plus–minus values are means ± SE. P values of between-group comparisons were determined by Student’s t-test or nonparametric Mann–Whitney U tests. P values of within-group comparisons were determined by ANOVA with 95 % CIs. ALT alanine aminotransferase, ANOVA analysis of variance, BUN blood urea nitrogen, CEA carcino-embryonic antigen, CI confidence interval, CRP C reactive protein, TBIL total bilirubin
\