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Fig. 3 | BMC Medicine

Fig. 3

From: Prevalence of genetic variants of keratins 8 and 18 in patients with drug-induced liver injury

Fig. 3

K8 K393R and K18 D89H variants result in keratin network disruption. a NIH 3T3 cells were transiently transfected with wild-type K8/K18 (WT) or a combination of K8/K18 variants and a WT partner keratin and stained with an anti-K18 antibody. Transfections were performed in triplicate. b The percentage of cells with disrupted keratin filaments was quantified. At least 100 cells were counted in each experiment

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