Table 4 Changes in laboratory parameters over time

Reticulocyte count (%)

1.7

1.3

0.051

3

1.9

0.0009

1.4

1.5

0.056

1

1.2

0.98

(0.6–3.8)

(0.5–4.5)

(1.6–3)

(0.6–7)

(0.9–4.8)

(0.3–6)

(0.5–2.4)

(0.4–2.6)

Plasma haemoglobin (g/dL)

0.1

0.085

0.3

0.05

0.05

0.81

0.03

0.04

0.75

0.08

0.08

0.9

(0.01–13.5)

(0.01–0.71)

(0.02–0.46)

(0–0.27)

(0.01–0.13)

(0–0.28)

(0.04–0.09)

(0–0.24)

Haptoglobin (g/L)

0.34

0.59

0.21

0.35

0.72

0.006

0.69

0.98

0.03

0.54

0.87

0.029

(0–1.48)

(0–2.16)

(0.09–1.07)

(0.1–1.83)

(0.16–1.19)

(0.04–2.32)

(0.08–1.25)

(0.06–2.22)

Low haptoglobin^a

8/16

14/56

0.056

5/14

8/57

0.11

2/14

3/52

0.28

5/14

4/49

0.02

(50)

(25)

(35.7)

(14.1)

(14.3)

(5.8)

(35.7)

(8.2)

LDH (IU/L)

308

231

0.01

350

196

0.0002

319.5

183.5

0.005

296.5

181

0.008

(127–800)

(23–611)

(178–700)

(58–783)

(121–619)

(37–593)

(154–746)

(118–522)

High LDH^a

13/17

18/56

0.002

12/15

12/57

0.000

10/14

7/52

0.001

8/14

7/49

0.002

(76.5)

(32.1)

(80)

(21.1)

(71.4)

(13.5)

(57.1)

(14.3)

Unconjugated bilirubin (mg/L)

2.5

3.75

0.63

1.7

1.7

0.9

1.4

1.4

0.66

1.45

1.5

0.59

(0.6–9.8)

(0.5–14.3)

(0.4–4.8)

(0.19–3.1)

(0.7–3.6)

(0.2–4.3)

(0.6–3.4)

(0.5–4.3)

Creatinine (μmol/L)

58

74

0.003

58

63

0.13

54.5

60.5

0.29

54.5

58

0.32

(28–86)

(35–90)

(28–83)

(28–85)

(19–82)

(27–99)

(24–80)

(26–84)