Skip to main content

Advertisement

Table 3 Univariate Cox regression modeling for the overall survival using each of the clinical parameters (A) and multivariate Cox regression modeling by combining four variables (P <0.05 in univariate analysis) (B) in validation set I. All the variables (except the metastasis site) were considered as continuous values

From: A robust blood gene expression-based prognostic model for castration-resistant prostate cancer

A. Univariate analysis of validation set I    
  Concordance index P value (Likelihood ratio test) P value (Logrank test)
Wang_4genescore 0.81 0.0006 7×10−05
Hemoglobin 0.75 0.001 0.001
VisceralMetastasis 0.58 0.006 1×10−05
LDH 0.72 0.043 0.016
BoneMetastasis 0.56 0.051 0.15
EosinophilCount 0.69 0.052 0.068
PSA 0.62 0.12 0.066
AP 0.61 0.18 0.13
NLRatio 0.57 0.18 0.14
MonocyteCount 0.46 0.19 0.11
PlateletCount 0.62 0.3 0.3
NeutrophilCount 0.50 0.4 0.4
Gleason 0.52 0.7 0.7
LymphocyteCount 0.59 0.7 0.7
BasophilCount 0.48 >0.9 >0.9
B. Multivariate analysis of validation set I  
  P value (Wald’s test)   
Wang_4genescore 0.045   
Hemoglobin 0.18   
visceralMets 0.13   
LDH 0.4