Skip to main content

Advertisement

Table 4 Summary results of model

From: Extending the elderly- and risk-group programme of vaccination against seasonal influenza in England and Wales: a cost-effectiveness study

Scenario Elderly- and risk-group No vaccination 2–4 y 50–64 y 5–16 y 2–4 & 50–64 y 2–16 y 2–16 & 50–64 y 2–64 y
Cases mean (000s) 5,325 6,474 4,914 4,668 2,882 4,269 2,559 1,971 322
Low 3,787 4,641 3,506 3,268 1,764 3,006 1,513 1,075 30
High 7,137 8,548 6,544 6,323 4,215 5,760 3,780 3,044 816
GP mean 603,095 721,152 539,893 541,134 313,892 480,317 264,246 207,979 37,544
Low 368,255 451,303 323,362 321,755 169,135 283,818 133,495 95,343 3,383
High 916,405 1,056,782 822,924 826,488 536,822 737,721 458,143 377,580 95,980
Hospitalisations mean 11,957 16,259 10,348 10,648 7,024 9,113 5,812 4,635 1,166
Low 6,861 9,439 5,951 5,993 3,279 5,079 2,509 1,778 59
High 19,152 26,641 16,820 17,307 12,299 14,952 10,468 8,753 3,223
Death mean 1,784 2,917 1,668 1,568 1,099 1,454 985 778 179
Low 643 1,081 602 573 346 530 289 198 6
High 3,930 6,440 3,677 3,386 2,507 3,180 2,268 1,887 625
Non death QALYs mean 40,514 49,365 37,375 35,495 21,896 32,450 19,446 14,946 2,429
Low 3,852 4,752 3,555 3,353 2,054 3,087 1,794 1,337 81
High 126,421 152,964 115,649 111,676 67,157 101,865 58,597 45,899 10,242
Death associated QALYs mean 13,554 21,660 12,684 11,932 8,371 11,073 7,508 5,936 1,316
Low 5,711 8,669 5,279 4,917 2,962 4,497 2,561 1,791 52
High 28,198 44,823 26,431 24,196 17,590 22,877 16,155 13,454 4,465
QALYs loss total mean 54,068 71,025 50,059 47,426 30,267 43,523 26,953 20,882 3,745
Low 13,253 19,358 12,387 11,767 7,954 10,915 6,940 5,336 380
High 141,995 177,528 131,318 125,105 76,379 114,248 68,559 52,870 11,601
Mean programme cost (£K) 134,817 149,012 187,054 191,283 201,248 205,477 257,714 418,988
Low 105,494 117,032 147,680 151,915 159,480 163,653 206,070 335,773
High 163,856 180,742 225,997 230,463 242,665 247,481 309,787 502,957
HC cost mean (£K) 32,607 40,664 28,886 29,184 17,669 25,615 14,788 11,687 2,378
Low 18,591 24,017 16,432 16,079 8,932 14,163 7,101 4,961 173
High 54,172 66,369 48,275 48,485 31,087 42,387 26,175 21,276 6,130
Cost total mean (£K) 167,425 40,664 177,898 216,238 208,952 226,863 220,265 269,401 421,366
Low 124,085 24,017 133,464 163,758 160,847 173,642 170,753 211,031 335,946
High 218,027 66,369 229,018 274,482 261,551 285,052 273,656 331,063 509,087
  1. The average annual number of influenza-like illness (febrile) cases, GP consultations, etc. are shown along with measures of their distribution for each of the strategies (columns)
  2. GP, General practitioner; QALY, Quality-adjusted life year