Skip to main content

Table 3 Validation cohort 2: clinical characteristics of patients for western blot experiment

From: Chemotherapy reduces PARP1 in cancers of the ovary: implications for future clinical trials involving PARP inhibitors

Patients

Number (%)

Number

74

Age(y), mean(range)

60.7 (24–87)

Histology

Serous

48 (64.9)

Non Serous

26 (35.1)

Stage

I

11 (16.4)

II

5 (7.5)

III

42 (62.7)

IV

9 (13.4)

Grade

1

9 (16.9)

2

5 (9.4)

3

39 (73.6)

Chemotherapy

Neo-adjuvant

34 (46)

Adjuvant

25 (34)

Surgery

Laparotomy

30 (46)

Laparoscopy

2 (3)

Robotic

33 (51)

Residual disease

8 (10.8)

Response

Responsive

33 (75)

Resistant

11 (25)

Recurrence

Number

27 (36.5)

Mean time (range)

9.6 months (3–29)

Deceased

Number

21 (31.3)

Mean time (range)

26.5 months (4–88)

Follow-up

Mean time (range)

31.4 months (7–107)