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Table 3 AUC, specificity, sensitivity, and accuracy of the ROC models (in %)

From: Metabolomic profiles of hepatocellular carcinoma in a European prospective cohort

  All Cases diagnosed <2 years Cases diagnosed ≥2 years
  AUC Spe Sen Acc AUC Spe Sen Acc AUC Spe Sen Acc
AFPa 73 65.3 71.9 67.5 81 79 77.3 78.5 71 60.9 74 65.3
Liver function scoreb 80 84.7 70.2 79.8 79 88.4 68.2 81.5 80 83.8 70.6 79.3
O-PLS scorec 85 81.5 71.1 78.1 93 83.7 86.4 84.6 79 74.9 68.5 72.7
O-PLS CV statusd 74 68 68.4 68.1 82 100 63.6 87.7 71 68.7 67.4 68.3
O-PLS CV status + AFPe 75 80.6 75.4 78.9 82 100 63.6 87.7 73 70.9 70.6 70.8
O-PLS CV status + liver scoref 82 68 68.4 68.1 84 86 77.3 83 80 83.8 70.7 79.3
  1. AUC, Area under the curve; Spe, Specificity; Sen, Sensitivity; Acc, Accuracy of the model
  2. aModel based on the serum AFP concentration
  3. bModel based on the liver function score
  4. cModel based on the score of the O-PLS analysis
  5. dModel based on the cross-validated (CV) case/control status of the O-PLS analysis
  6. eCombination between the CV status of the O-PLS and the AFP variable
  7. fCombination between the CV status of the O-PLS and the liver function score