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Fig. 2 | BMC Medicine

Fig. 2

From: Neoadjuvant trials in early breast cancer: pathological response at surgery and correlation to longer term outcomes – what does it all mean?

Fig. 2

Associations between three definitions of pathological complete response and event-free survival and overall survival. We compared event-free survival and overall survival between patients who did and did not achieve a pathological complete response according to one of three definitions. Patients who did not achieve pathological complete response are not shown. The number of patients who achieved a pathological complete response is listed for each pathological complete response definition. Patients could achieve pathological complete response according to more than one definition. ypT0ypN0 = absence of invasive cancer and in situ cancer in breast and axillary nodes. ypT0/is ypN0 = absence of invasive cancer in breast and axillary nodes, irrespective of ductal carcinoma in-situ. ypT0/is = absence of invasive cancer in breast, irrespective of ductal carcinoma in-situ or nodal involvement. CI confidence interval, HER2 human epidermal growth factor receptor 2, HR hazard ratio. (Reproduced with permission from The Lancet, Cortazar et al. [5]: License Number 3666940645625)

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