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Table 3 Indicative proportion of early outbreak prevented by implementing different vaccination strategies: prospective versus reactive vaccination of healthcare workers

From: Role of healthcare workers in early epidemic spread of Ebola: policy implications of prophylactic compared to reactive vaccination policy in outbreak prevention and control

      Percentage of initial outbreak prevented by vaccination strategy
Epidemic Country Total number of cases [4] Total number of deaths [4] Cases included in epidemic tree Strategy 1: Vaccinate prophylactically (100 % coverage) Strategy 2: Vaccinate prophylactically approx. 75 % of HCWs Strategy 3: Vaccinate reactively (lag-time 42 days)
2014 West Africa Guinea [22] 3,792 2,530 71 61 % (43/71) 36.6 % (26/71) 0
  Liberia [2428] 10,672 4,808 9 67 % (6/9) 11 % (1/9) 0
  Sierra Leone [2931] 13,683 3,953 NR NR NR 0
  Nigeria [23] 20 8 20 80 % (16/20) 50 %(10/20) 0
  Mali [3234] 8 6 8 38 % (3/8) 13 % (1/8) 0
  USA [35] 4 1 4 75 % (3/4) 50 % (2/4) 0
  UK [36] and Spain [37] 2 0 2 100 % (2/2) 50 % (1/2) 0
  Senegal [38] 1 0 1 0 0 0
  Overall 28,183 11,306 115 63.5 % (73/115) 35.7 % (41/115)  
  (95 % confidence interval)     (0.54–0.72) (0.27–0.45)  
Historic outbreaks Kikwit [6, 3943] 315 250 9 100 % (9/9) NR NR
  Mosango [44] 23 18 23 100 % (23/23) 74 % (17/23) NR
  Yambuku [2] 318 280 45 44 % (20/45) NR NR
Total     192 65.1 % (125/192) 42.0 % (58/138) 0.0 % (0/609)
(95 % confidence interval)      (0.58–0.72) (0.34–0.51)  
  1. Cases numbers accurate as of 06/09/2015
  2. NR, Not reported