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Table 4 Correlation of severity of traction bronchiectasis with HRCT pattern extents and fibroblastic foci scores on multivariate linear regression within disease subgroups

From: Relationship between fibroblastic foci profusion and high resolution CT morphology in fibrotic lung disease

  HRCT pattern Partial regression coefficient P value 95 % CI
*IPF/UIP (n=70) r2 = 0.34 FF score 0.49 <0.0001 0.17–0.80
Global disease extent −0.02 0.74 −0.12–0.08
Extent of reticulation 0.04 0.03 0.00–0.08
Extent of ground glass 0.01 0.09 −0.02–0.03
Extent of honeycombing 0.02 0.61 −0.05–0.08
Extent of consolidation −0.26 0.63 −1.30–0.79
Extent of emphysema −0.31 0.05 −0.60– −0.01
*Fibrotic NSIP (n=43) r2 = 0.58 FF score 0.29 0.29 −0.27–0.86
Global disease extent 0.03 <0.0001 0.02–0.69
Extent of reticulation 0.03 0.27 −0.02–0.08
Extent of ground glass 0.004 0.60 −0.01–0.02
Extent of honeycombing 0.01 0.76 −0.07–0.09
Extent of consolidation 0.04 0.74 −0.66–0.91
Extent of emphysema −0.31 0.04 −0.60– −0.01
CHP (n=49) r2 = 0.35 FF score 0.72 <0.0001 0.43–1.00
Global disease extent −0.02 0.67 −0.13–0.08
Extent of reticulation 0.03 0.27 −0.02–0.08
Extent of ground glass 0.004 0.60 −0.01–0.02
Extent of honeycombing 0.01 0.76 −0.07–0.09
Extent of consolidation 0.04 0.74 −0.66–0.91
Extent of emphysema −0.73 0.05 −1.46– −0.01
  1. *Fibrotic NSIP group = idiopathic fibrotic NSIP (n=25) and CTD-NSIP (n=18) combined. NSIP= non-specific interstitial pneumonia. *IPF/UIP =idiopathic pulmonary fibrosis and connective tissue disease related usual interstitial pneumonia combined. CHP=chronic hypersensitivity pneumonitis
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