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Table 4 Correlation of severity of traction bronchiectasis with HRCT pattern extents and fibroblastic foci scores on multivariate linear regression within disease subgroups

From: Relationship between fibroblastic foci profusion and high resolution CT morphology in fibrotic lung disease

 

HRCT pattern

Partial regression coefficient

P value

95 % CI

*IPF/UIP (n=70) r2 = 0.34

FF score

0.49

<0.0001

0.17–0.80

Global disease extent

−0.02

0.74

−0.12–0.08

Extent of reticulation

0.04

0.03

0.00–0.08

Extent of ground glass

0.01

0.09

−0.02–0.03

Extent of honeycombing

0.02

0.61

−0.05–0.08

Extent of consolidation

−0.26

0.63

−1.30–0.79

Extent of emphysema

−0.31

0.05

−0.60– −0.01

*Fibrotic NSIP (n=43) r2 = 0.58

FF score

0.29

0.29

−0.27–0.86

Global disease extent

0.03

<0.0001

0.02–0.69

Extent of reticulation

0.03

0.27

−0.02–0.08

Extent of ground glass

0.004

0.60

−0.01–0.02

Extent of honeycombing

0.01

0.76

−0.07–0.09

Extent of consolidation

0.04

0.74

−0.66–0.91

Extent of emphysema

−0.31

0.04

−0.60– −0.01

CHP (n=49) r2 = 0.35

FF score

0.72

<0.0001

0.43–1.00

Global disease extent

−0.02

0.67

−0.13–0.08

Extent of reticulation

0.03

0.27

−0.02–0.08

Extent of ground glass

0.004

0.60

−0.01–0.02

Extent of honeycombing

0.01

0.76

−0.07–0.09

Extent of consolidation

0.04

0.74

−0.66–0.91

Extent of emphysema

−0.73

0.05

−1.46– −0.01

  1. *Fibrotic NSIP group = idiopathic fibrotic NSIP (n=25) and CTD-NSIP (n=18) combined. NSIP= non-specific interstitial pneumonia. *IPF/UIP =idiopathic pulmonary fibrosis and connective tissue disease related usual interstitial pneumonia combined. CHP=chronic hypersensitivity pneumonitis