Skip to main content
Fig. 3 | BMC Medicine

Fig. 3

From: Serum survivin predicts responses to treatment in active rheumatoid arthritis: a post hoc analysis from the SWEFOT trial

Fig. 3

Core set clinical parameters in the survivin subgroups of the SWEFOT trial. At baseline, all patients were treated with methotrexate (MTX). a At 3 months, the patients with a disease activity score (DAS28) < 3.2 proceeded on MTX monotherapy. b The patients with a DAS28 > 3.2 were randomized to triple therapy with MTX + sulfasalazine (SSZ) + hydroxychloroquine (HCQ), c or to anti-TNF therapy (MTX + infliximab). The intention-to-treat analysis was conducted for clinical parameters, including the DAS28, functional disability (Health Assessment Questionnaire, HAQ), pain perception with the visual analog scale (pain-VAS), and the patient’s global assessment of disease activity (PtGA-VAS). Boxes represent the 25th to 75th percentile of the group, and horizontal lines within the boxes indicate median values. Four groups of patients were compared: patients positive for survivin (PP), and negative for survivin (NN) at baseline and over 24 months; patients positive for survivin at baseline who converted negative (PN), and negative for survivin who converted positive (NP) over 24 months. Comparisons of the absolute values were done by Mann–Whitney U tests

Back to article page