Skip to main content

Table 3 Selected gene expression signatures that are highly expressed in young breast cancer patients

From: Genomic aberrations in young and elderly  breast cancer patients

Signature

Logistic regressionb

FDR

Endocrine resistance

 Creighton_Endocrine_Therapy_Resistancea

1.03E-18

1.07E-14

 Massarweh_Tamaxifen_Resistance

1.79E-14

1.84-10

 Masri_resistance_to Tamoxifen_And_Aromatase_Inhibitor

7.58E-09

7.66E-05

Proliferation

 Regulation of cell cycle

1.43E-11

1.47E-07

 Regulation of Mitotic_Cell_Cycle

8.43E-10

8.59E-06

Stem cell

 Lim_Mammary_Stem_Cell

3.62E-08

0.0003

 PID_Notch_Pathway

1.52E-11

1.56E-07

 Benporath_SOX2_Targets

1.58E-10

1.62E-06

 Galie_Tumor_Stemness_Genes

1.62E-07

0.001

 Notch_Signaling_Pathway

1.00E_06

0.009

 Nguyen_Notch_Targets_Up

1.12E-06

0.01

  1. aMore than one signature; bmodel adjusted for tumor size, nodal status, tumor histology and breast cancer subtype. FDR, false discovery rate