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Fig. 3 | BMC Medicine

Fig. 3

From: Renal medullary (pro)renin receptor contributes to angiotensin II-induced hypertension in rats via activation of the local renin–angiotensin system

Fig. 3

Effect of intramedullary (pro)renin receptor (PRR) inhibition on renal inner medullary expression of cytokines during angiotensin II (AngII)-induced hypertension in rats. a, b The expression of tumor necrosis factor alpha (TNF-α) and interleukin 18 (IL-18) in the inner medulla of control (CTR), AngII, and AngII + intramedullary PRO20-infused (AngII + IM RPO20) rats was determined by quantitative reverse transcriptase polymerase chain reaction, which is normalized by glyceraldehyde 3-phosphate dehydrogenase (GAPDH). N = 6 per group. Data are mean ± standard error

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