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Fig. 5 | BMC Medicine

Fig. 5

From: Renal medullary (pro)renin receptor contributes to angiotensin II-induced hypertension in rats via activation of the local renin–angiotensin system

Fig. 5

Effect of intramedullary (pro)renin receptor (PRR) inhibition on renal inner medullary prorenin/renin expression in angiotensin II (AngII)-infused rats. The expression of prorenin/renin in the inner medulla was determined by using enzyme-linked immunosorbent assay (ELISA) and quantitative reverse transcriptase polymerase chain reaction (qRT-PCR) determined in Control (CTR), AngII, or AngII + intramedullary PRO20-infused (AngII + IM RPO20) rats. a ELISA detection of prorenin/renin content. b qRT-PCR detection of renin mRNA expression. N = 5–6 per group. Data are means ± standard error

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