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Fig. 7 | BMC Medicine

Fig. 7

From: Renal medullary (pro)renin receptor contributes to angiotensin II-induced hypertension in rats via activation of the local renin–angiotensin system

Fig. 7

Effect of angiotensin II (AngII) on prorenin/renin content, soluble (pro)renin receptor (sPRR) content and renin activity in rat vascular smooth muscle cells (VSMCs). The cells were exposed to 100 nM AngII for 24 h and medium prorenin/renin content (a) and sPRR content (b) was analyzed by enzyme-linked immunosorbent assay. Medium renin activity (c) was analyzed by measurement of AngI generation in the absence of substrate. N = 12 per group. Data are means ± standard error. CTR control

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