TY - JOUR AU - Undén, Linda AU - Calcagnile, Olga AU - Undén, Johan AU - Reinstrup, Peter AU - Bazarian, Jeff PY - 2015 DA - 2015/12/09 TI - Validation of the Scandinavian guidelines for initial management of minimal, mild and moderate traumatic brain injury in adults JO - BMC Medicine SP - 292 VL - 13 IS - 1 AB - Acute management of traumatic brain injury (TBI), in particular mild TBI, focuses on the detection of the 5–7 % who may be harboring potentially life-threatening intracranial hemorrhage (IH) using CT scanning. Guidelines intending to reduce unnecessary head CT scans using available clinical variables to detect those at high IH risk have shown varying results. Recently, the Scandinavian Neurotrauma Committee (SNC) derived a new set of high-IH risk variables for adults with TBI using an evidence-based literature review. Unlike previous guidelines, the SNC guideline incorporates serum values of the brain protein S100B with clinical variables. SN - 1741-7015 UR - https://doi.org/10.1186/s12916-015-0533-y DO - 10.1186/s12916-015-0533-y ID - Undén2015 ER -