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Fig. 4 | BMC Medicine

Fig. 4

From: Randomized trial of primaquine hypnozoitocidal efficacy when administered with artemisinin-combined blood schizontocides for radical cure of Plasmodium vivax in Indonesia

Fig. 4

Changes in liver and blood chemistry and QTc values prior to and up to 63 days following treatment commencement of therapy. Graphs illustrating liver and blood laboratory values and QTc measurements that significantly altered after the commencement of therapy among groups. Each graph shows median (horizontal line), interquartile range (box), 1.5 times that range (horizontal line), and outlying observations (points). The lightly shaded area shows the range of normal values, except for ΔQTc which reflects the mean ΔQTc ± standard deviation. MetHb measurements for AS + PQ represent days post-dosing with PQ (commencing on day 9 post-patency). MetHb methemoglobin, AS artesunate, PQ primaquine

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