Table 2 The incidence of invasive meningococcal disease (IMD) and relative risk by demographics for persons diagnosed with HIV and for the uninfected population in England during 2011–2013
Persons diagnosed with HIV | Uninfected population | ||||||||
|---|---|---|---|---|---|---|---|---|---|
Cases | Person-years | Incidence | Cases | Person-years | Incidence | Relative risk | 95 % CI | P value | |
Overall | 14 | 213,725 | 6.6 | 2,339 | 160,252,992 | 1.5 | 4.5 | (2.7, 7.5) | <0.001 |
Age at meningococcal infection (years) | |||||||||
<16 | 1 | 2,415 | 41.4 | 1,395 | 30,366,823 | 4.6 | 9.0 | (1.3, 64.0) | 0.008 |
16–24 | 3 | 6,703 | 44.8 | 314 | 18,760,191 | 1.7 | 26.5 | (8.6, 81.8) | <0.001 |
25–44 | 5 | 113,183 | 4.4 | 159 | 43,536,541 | 0.4 | 11.8 | (5.0, 27.9) | <0.001 |
45–65 | 5 | 84,462 | 5.9 | 225 | 40,505,320 | 0.6 | 10.4 | (4.4, 24.9) | <0.001 |
≥65 | 0 | 6,962 | 0.0 | 238 | 27,084,317 | 0.9 | |||
Not reported | 8 | ||||||||
Sex | |||||||||
Male | 7 | 142,479 | 4.9 | 1,166 | 78,858,090 | 1.5 | 3.3 | (1.6, 6.9) | <0.001 |
Female | 7 | 71,246 | 9.8 | 1,159 | 81,394,902 | 1.4 | 6.9 | (3.3, 14.4) | <0.001 |
Not reported | 14 | ||||||||
Year of meningococcal diagnosis | |||||||||
2011 | 6 | 67,649 | 8.9 | 880 | 53,039,551 | 1.7 | 5.3 | (2.4, 11.8) | <0.001 |
2012 | 3 | 71,316 | 4.2 | 738 | 53,422,384 | 1.4 | 3.0 | (1.0, 9.4) | 0.043 |
2013 | 5 | 74,760 | 6.7 | 721 | 53,791,057 | 1.3 | 5.0 | (2.1, 11.9) | <0.001 |