| Coefficienta | 95 % CI | HRa | 95 % CI |
---|---|---|---|---|
Age, per year increase | 0.055 | 0.047 to 0.062 | 1.06 | 1.05 to 1.06 |
Age2, per unit increase | −0.005 | −0.007 to −0.004 | 0.995 | 0.993 to 0.996 |
Gender (female v male) | 0.160 | 0.104 to 0.216 | 1.17 | 1.11 to 1.24 |
Calendar year, per year increase | 0.074 | 0.063 to 0.084 | 1.08 | 1.07 to 1.09 |
BMI (kg/m2), per unit increase | −0.050 | −0.063 to-0.036 | 0.95 | 0.94 to 0.96 |
Current anti-hypertensive use (yes vs. no) | −0.249 | −0.301 to −0.197 | 0.78 | 0.74 to 0.82 |
Systolic blood pressure (mmHg), per unit increase | −0.006 | −0.008 to −0.005 | 0.994 | 0.992 to 0.995 |
Lipid ratio (per unit increase) | 0.042 | −0.055 to 0.138 | 1.04 | 0.95 to 1.15 |
Smoking status | Â | Â | Â | Â |
Never | 0 | Â | 1 | Â |
Past | −0.178 | −0.233 to −0.122 | 0.84 | 0.79 to 0.89 |
Current | −0.134 | −0.229 to −0.039 | 0.88 | 0.80 to 0.96 |
History of alcohol problem (yes vs. no) | 0.256 | −0.009 to 0.521 | 1.29 | 0.99 to 1.68 |
History of diabetes (yes vs. no) | 0.183 | 0.102 to 0.264 | 1.20 | 1.11 to 1.30 |
History of stroke or transient ischemic attack (yes vs. no) | 0.242 | 0.177 to 0.306 | 1.27 | 1.19 to 1.36 |
History of atrial fibrillation (yes vs. no) | 0.057 | −0.018 to 0.132 | 1.06 | 0.98 to 1.14 |
Current depression/use of anti-depressants (yes vs. no) | 0.400 | 0.335 to 0.465 | 1.49 | 1.40 to 1.59 |
Current anxiety/use of anxiolytics (yes vs. no) | 0.136 | 0.034 to 0.237 | 1.15 | 1.04 to 1.27 |
Current NSAID use, excluding aspirin (yes vs. no) | −0.157 | −0.237 to −0.078 | 0.86 | 0.79 to 0.93 |
Current aspirin use (yes vs. no) | 0.092 | 0.037 to 0.147 | 1.10 | 1.04 to 1.16 |