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Table 5 Risk classification using the 60–79 years dementia risk algorithm when applied to validation cohort

From: Predicting dementia risk in primary care: development and validation of the Dementia Risk Score using routinely collected data

Cut off for high risk Sensitivity Specificity PPV NPV Patients classified as high risk, n (%) Patients classified as high risk who develop dementia, n (%) Patients classified as low risk, n (%) Patients classified as low risk who develop dementia, n (%)
1 % 77.70 73.05 2.14 99.77 61,803 (27.33) 1,320 (2.14) 164,337 (72.67) 379 (0.23)
2 % 58.36 85.15 2.89 99.63 34,323 (15.18) 992 (2.89) 191,817 (84.82) 707 (0.37)
5 % 19.39 97.03 4.71 99.38 6,989 (3.09) 329 (4.71) 219,151 (96.91) 1,370 (0.62)
10 % 5.62 99.52 8.20 99.29 1,164 (0.51) 95 (8.2) 224,976 (99.49) 1,604 (0.71)
20 % 0.72 99.96 10.87 99.25 113 (0.05) 12 (10.87) 226,027 (99.95) 1,687 (0.75)
  1. PPV, Positive predictive value; NPV, Negative predictive value