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Table 3 Description of the seven patients with false benign malignancies

From: Long- versus short-interval follow-up of cytologically benign thyroid nodules: a prospective cohort study

Subject no.

Time until first follow-up, years

Nodule size at initial aspiration, cm

Nodule size at first follow-up, cm

Thyroidectomy indication

Histopathology

Encapsulated

Lymphovascular invasion/Extrathyroidal extension

Lymph node/Distant metastases

Clinical status

1

1.0

5.2

6.1

Compressive symptoms

PTC follicular variant 5.0 cm

Encapsulated a

1 Focus suspicious for LVI

1 Scapular metastasisc

Disease free with no recurrence

2

1.3

4.0

4.5

Abnormal repeat cytology

PTC follicular variant 4.3 cm

Encapsulated

No

No

Disease free with no recurrence

3

1.4

2.9

4.4

Compressive symptoms

PTC follicular variant 3.3 cm

Encapsulated

No

No

Disease free with no recurrence

4

2.3

2.0

2.9

Abnormal repeat cytology

PTC follicular variant 3.8 cm

Encapsulated b

No

No

Disease free with no recurrence

5

2.7

1.2

1.6

Abnormal repeat cytology

PTC follicular variant 1.1 cm

Encapsulated

No

No

Disease free with no recurrence

6

3.7

2.2

2.7

Abnormal repeat cytology

PTC follicular variant 2.5 cm

Encapsulated

No

No

Disease free with no recurrence

7

4.4

4.5

6.1

Abnormal repeat cytology

PTC follicular variant 5.5 cm

Partially-encapsulated/ well-circumscribed

No

No

Disease free with no recurrence

  1. aWith focal capsular invasion
  2. bWith extensive capsular invasion
  3. cMetastasis showed excellent reaction to radioactive iodine treatment
  4. PTC, Papillary thyroid carcinoma; LVI, Lymphovascular invasion