Fig. 4

Variability in the impact of annual mass drug administration (MDA) and combined MDA plus vector control (VC) on intervention rounds in years required to eliminate LF in different endemic communities (results shown for selected study sites). The required annual MDA rounds without and with VC as a function of drug coverage (from 40 % to 100 %) are shown as box plots, with the solid horizontal line depicting the means. Supplemental use of vector control (VC) was modelled at 80 % coverage. The results are shown for mf breakpoint threshold values representing a 95 % elimination probability (see Table 3). The results for the remaining study sites are shown in Additional file 1: Figure S4 and S5. These results are from the model simulations carried out for both LF intervention scenarios using the site-specific parameter vectors that best-fitted baseline age-prevalence infection in each site (compare with Fig. 1)