Skip to main content

Table 1 Description of baseline survey data. The study sites are given with the baseline sample size and microfilariae (mf) prevalence (%), blood volumes collected during the survey to test for mf positivity, annual biting rate (ABR) of vector mosquitoes, dominant vector species and drug regimen used for simulating the chemotherapeutic interventions by mass drug administration (MDA) without/with vector control (VC)

From: Heterogeneous dynamics, robustness/fragility trade-offs, and the eradication of the macroparasitic disease, lymphatic filariasis

Study villages Sample size Blood volume (μl) aMf (%) bBaseline ABR Mosquito species (genus) cDrug regimen dDrug efficacies (ω, ε, P) Source
Peneng 63 1,000 66.67 8,194 An DEC + ALB (55, 95, 6) [8, 11, 78, 79]
Albulum 50 1,000 80 42,328 An DEC + ALB (55, 95, 6) [8, 11, 78, 79]
Yauatong 131 1,000 92.37 37,052 An DEC + ALB (55, 95, 6) [8, 11, 78, 79]
Nanaha 211 1,000 54.98 11,611 An DEC + ALB (55, 95, 6) [8, 11, 78, 79]
Ngahmbule 346 1,000 51.16 4,346 An DEC + ALB (55, 95, 6) [8, 11, 78, 79]
Masaika 848 100 28.61 6,184 An IVM + ALB (35, 99, 9) [80]
Tawalani 367 100 35.72 12,850 An IVM + ALB (35, 99, 9) [16]
Jaribuni 1,007 100 25.35 15,677 An IVM + ALB (35, 99, 9) [81, 82]
Tingrela 699 20 63.89 4,156 An IVM + ALB (35, 99, 9) [83]
Chiconi 245 20 58.90 10,586 An IVM + ALB (35, 99, 9) [84]
Kingwede 825 100 3.07 1,548 Cx IVM + ALB (35, 99, 9) [80]
Mao 546 100 27.8 25,439 Cx IVM + ALB (35, 99, 9) [16]
Mambrui 787 100 24.99 4,964 Cx IVM + ALB (35, 99, 9) [81, 82]
Pondicherry 1,549 20 34.74 88,500 Cx DEC + ALB (55, 95, 6) [85]
Calcutta 861 20 26.72 115,942 Cx DEC + ALB (55, 95, 6) [86, 87]
Vettavallam 7,976 20 22.83 100,375 Cx DEC + ALB (55, 95, 6) [88]
Pakistan 1,443 20 31.49 1,607 Cx DEC + ALB (55, 95, 6) [89, 90]
Jakarta 922 20 12.27 223,000 Cx DEC + ALB (55, 95, 6) [91]
  1. aAll mf prevalence values were standardized to reflect sampling of 1 ml blood volumes using a transformation factor of 1.95 and 1.15, respectively, for values originally estimated using 20 or 100 μl blood volumes [49]; bbaseline ABR can be used to get monthly biting rate (MBR = ABR/12); cthe combination drug regimens are recommended by the WHO [92, 93]; dthe drug efficacy values are taken from [36]. An, Anopheles mosquitoes; Cx, Culex mosquitoes; drug efficacies (ω, ε, P) (instantaneous kill rate (%) for adult worms, instantaneous kill rate (%) for microfilariae, drug efficacy period in months); mf (%), microfilariae prevalence in percentages calculated from the number of mf-positive samples out of the total individuals sampled (sample size) in a study site. ALB, albendazole; DEC, diethylcarbamazine citrate; IVM, ivermectin