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Fig. 4 | BMC Medicine

Fig. 4

From: Mycobacterium tuberculosis whole genome sequencing and protein structure modelling provides insights into anti-tuberculosis drug resistance

Fig. 4

Mutations in binding site regions. a depicts the spatial distribution of mutated residues in the rpoB-RMP complex while (b) shows the residue Ser315 in katG-INH complex (residues depicted with carbons in green). The distance between the residues and the ligands (depicted with carbons in dark grey) vary from 2.1 to 5.7 Å. RMP rifampicin, INH isoniazid

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