Table 2 Second-line drug related mutations in candidate genes

Para-aminosalisylic acid

6

folC (E40G[1], I43G[1], D135G[1]);

thyA ( Y94C[1], Q97R[1], V135F[1]);

thyX promoter (G16A [2], T43G [1]).

Ethionamide

7

ethA (R469P[1]);

ethR-fabG1 promoter (C15T[6]);

inhA (S94[1])

Ofloxacin

3

gyrA (D94G [2]; N499D [1]).

Capreomycin

2

rrs (A1205G[1]); tlyA (G196E [1])