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Table 2 Study participant risk factors and microscopy and culture/drug-susceptible tuberculosis results

From: Rationing tests for drug-resistant tuberculosis – who are we prepared to miss?

  All subjects Sputum culture negative for TB Sputum culture positive for TB
Drug-susceptible TB MDR-TB Mono-resistant TB
  Unknown (n) n   Unknown (n) n   Unknown (n) n   Unknown (n)
n n Percentage of all subjects Percentage of all subjects Percentage of all drug sensitive TB patients Percentage of all subjects Percentage of all MDR-TB patients Percentage of all subjects Percentage of all mono-resistant TB patients
All patients 1,545 1,398 90.5 0 115 7.4 100 0 20 1.3 100 0 12 0.8 100 0
≥1 MDR-TB-TB risk factora 553 506 32.8 0 32 2.1 27.8 0 11 0.7 55.0 0 4 0.3 33.3 0
≥1 MDR-TB risk factor or smear Positive sputumb 604 509 32.9 0 74 4.8 64.3 0 16 1.0 80.0 0 5 0.3 41.7 0
Previous TB 309 278 18.0 4 20 1.3 17.4 0 8 0.5 40.0 0 3 0.2 25.0 0
Known contact with MDR TB 161 153 9.9 8 3 0.2 2.6 0 3 0.2 15.0 0 2 0.1 16.7 0
Health worker 66 62 4.0 4 3 0.2 2.6 0 1 0.1 5.0 0 0 0.0 0.0 0
Current/ex prison worker or resident 38 32 2.1 4 5 0.3 4.3 0 1 0.1 5.0 0 0 0.0 0.0 0
HIV infection 18 18 1.2 4 0 0.0 0.0 1 0 0.0 0.0 0 0 0.0 0.0 0
  1. a MDR-TB risk factors as recommended by the WHO [10]; Previous TB treatment, Contact with known MDR-TBpatient), exposure to environments with high rates MDR TB (health care workers, prison workers & residents, previous hospitalisation), HIV infection
  2. bRepresents DST use as a follow on test after sputum microscopy
  3. TB, Tuberculosis; MDR-TB, Multidrug-resistant tuberculosis