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Table 3 Fully adjusted estimates for the association between homelessness and unsuccessful outcome of treatment of newly diagnosed PTB by logistic regression model (n = 36,604, complete case analysis)

From: The impact of being homeless on the unsuccessful outcome of treatment of pulmonary TB in São Paulo State, Brazil

  

Values

Adjusted OR (95 % CI)

P value

Exposure

Homelessness

No

Reference

<0.001

Yes

4.96 (4.27-5.76)

 

Adjusted for

Age, years

15-25

Reference

<0.001

  

25.1-35

1.01 (0.93-1.10)

Pdep < 0.001

  

35.1-45

0.93 (0.85-1.02)

 
  

45.1-55

0.84 (0.76-0.93)

 
  

55.1-65

0.94 (0.83-1.06)

 
  

65.1-75

1.08 (0.92-1.27)

 
  

75.1-85

1.92 (1.56-2.36)

 
  

85.1-105

2.47 (1.62-3.76)

 
 

Gender

Female

Reference

<0.001

  

Male

1.32 (1.23-1.41)

 
 

Country of birth

Brazil

Reference

<0.001

  

Not-Brazil

2.09 (1.74-2.51)

 
 

Race

White

Reference

0.001

  

Black

1.16 (1.06-1.28)

 
  

Mixed/Brown

1.08 (1.01-1.15)

 
  

Asian

0.82 (0.59-1.13)

 
  

Indigenous

1.48 (1.10-1.99)

 
 

Education

Illiterate

Reference

<0.001

  

1-3 years

1.04 (0.88-1.23)

Pdep < 0.001

  

4-7 years

1.07 (0.92-1.25)

 
  

8-11 years

0.84 (0.72-0.99)

 
  

12-14 years

0.57 (0.46-0.70)

 
  

> = 15 years

0.62 (0.48-0.81)

 
 

Alcohol

No

Reference

<0.001

  

Yes

1.33 (1.23-1.44)

 
 

Diabetes mellitus

No

Reference

0.173

  

Yes

0.92 (0.81-1.04)

 
 

Drug users

No

Reference

<0.001

  

Yes

2.06 (1.89-2.24)

 
 

Mental disorder

No

Reference

0.441

  

Yes

1.10 (0.87-1.38)

 
 

Other immunosuppression

No

Reference

0.144

  

Yes

1.29 (0.92-1.79)

 
 

Place of diagnosis

PHC/Ambulatory

Reference

<0.001

  

Emergency service

1.54 (1.44-1.65)

 
  

Hospital

1.89 (1.73-2.06)

 
 

Chest x-ray

Not done

Reference

<0.001

  

Normal

0.96 (0.80-1.15)

 
  

Additional pathology

1.07 (0.64-1.79)

 
  

Suggestive of TB

1.04 (0.95-1.14)

 
  

Cavitation

0.86 (0.78-0.96)

 
 

Microbiologic status

Negative

Reference

0.048

  

Positive

0.92 (0.85-1.00)

 
 

Initial drug scheme

Other

Reference

<0.001

  

RHZ

0.73 (0.59-0.91)

 
  

RHZE

0.65 (0.53-0.80)

 
 

Directly observed treatment-DOT

No

Reference

<0.001

  

Yes

0.45 (0.42-0.48)

 
  1. OR odds ratio, CI confidence interval, P dep test for departure from linearity, PHC primary health clinics, R rifampicin, H isoniazid, Z pyrazinamide and E ethambutol