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Table 1 Demographic and cardiovascular risk characteristics of the D:A:D cohort over time. The information shown in the table describes the current status of each individual under follow-up on 1 January each year (based on the last available measurement for that individual prior to the start of the year)

From: Is there continued evidence for an association between abacavir usage and myocardial infarction risk in individuals with HIV? A cohort collaboration

   Individuals under follow-up on 1 January of year:
   2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012
N   3,508 20,868 22,816 25,694 27,148 28,526 29,570 30,549 31,832 35,146 34,438 32,662 31,112
Male (%)   79.8 75.2 75.5 74.7 74.1 73.3 73.0 72.8 73.1 73.2 73.5 73.5 73.6
Age (years) Median 39 39 40 41 42 43 44 45 46 47 48 49 50
Previous AIDS (%)   25.9 25.8 26.3 26.3 26.6 26.7 26.8 27.1 26.9 26.5 26.9 27.5 27.8
10-year CVD risk (%) Low 5.1 35.7 42.3 45.4 49.5 52.8 57.0 61.9 64.2 63.9 66.8 69.8 71.7
  Moderate 1.7 7.8 9.1 8.8 9.1 9.3 9.1 9.2 9.9 10.5 10.7 11.0 11.3
  High 2.8 4.6 5.3 5.1 5.2 5.1 4.8 4.9 5.3 5.4 5.6 5.8 6.0
  Unknown 90.7 51.9 43.4 40.7 36.2 32.8 29.2 24.0 20.7 20.2 16.9 13.4 11.1
Smoking statusa Current smoker 27.2 49.2 49.6 49.0 47.2 47.5 45.5 45.0 44.1 43.8 42.7 41.0 39.8
Ex-smoker 50.6 21.4 21.8 20.8 22.2 22.4 24.7 25.3 26.1 26.1 27.5 29.3 30.6
  Never smoked 22.3 29.4 28.6 30.2 30.6 30.0 29.8 29.7 29.8 30.1 29.9 29.7 29.6
Family history of CVD (%) 5.1 8.7 8.7 8.3 8.2 8.1 8.0 8.0 7.7 7.3 7.5 7.7 7.8
Diabetes (%)   3.6 3.9 4.5 4.7 5.1 5.0 5.0 5.0 5.1 5.2 5.6 5.9 6.3
TC (mmol/L) Median 5.1 5.1 5.1 5.0 5.0 4.9 4.9 4.8 4.8 4.9 4.9 4.9 5.0
HDL-C (mmol/L) Median 1.1 1.1 1.1 1.2 1.2 1.2 1.2 1.2 1.2 1.2 1.2 1.2 1.2
TG (mmol/L) Median 1.9 1.7 1.7 1.7 1.7 1.6 1.6 1.5 1.5 1.5 1.5 1.5 1.5
CD4 (cells/mm3) Median 380 448 461 465 460 460 468 480 494 503 527 548 566
Viral load (log10 copies/ml) Median 2.4 2.1 1.9 1.8 1.7 1.7 1.7 1.7 1.7 1.7 1.7 1.7 1.7
  1. aExpressed as a proportion of those with known smoking status, which has increased from 71.9 % of the cohort in 2000 to 89.5 % in 2012. CVD cardiovascular disease, HDL-C high-density lipoprotein cholesterol, TC total cholesterol, TG triglycerides