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Table 1 Baseline characteristics of children by subsequent tuberculosis (TB) status

From: Tuberculosis incidence is high in HIV-infected African children but is reduced by co-trimoxazole and time on antiretroviral therapy

  TB No TB Total P value
  69 (7 %) 900 (93 %) 969  
Age (at baseline)
 Median, IQR (years) 5 (2–11) 5 (2–9)   
  < 3 years 31 (9) 307 (91) 338 0.07
Sex
 Male 28 (6) 460 (94) 488 0.09
 Female 41 (9) 440 (91) 481  
Centre
 Entebbe 16 (9) 163 (91) 179 0.35
 JCRC 16 (6) 248 (94) 264  
 Harare 14 (6) 243 (94) 257  
 PIDC 23 (9) 246 (91) 269  
Height (median IQR)
 Height-for-age Z score −3.0 (−4.0 to –1.8) −2.3 (−3.3 to –1.3)   <0.001
Weight (median IQR)
 Weight-for-age Z score −2.8 (−4.1 to –1.8) −1.8 (−2.8 to –0.9)   <0.001
WHO stage
 3 or 4 52 (8) 561 (92) 613 0.03
CD4 (median, IQR)
 CD4 % 8 (5–13) 13 (7–19)   0.001
 CD4 counta 136 (33–250) 253 (93–405)   0.07
Initial ART
 3TC ABC EFV 6 (6) 99 (94) 105 0.03
 3TC ABC NVP 24 (11) 190 (89) 214  
 ZDV 3TC ABC EFV 9 (4) 217 (96) 226  
 ZDV 3TC ABC NVP 30 (7) 394 (93) 30  
Randomization
 A (3TC/ABC/NNRTI throughout) 30 (9) 289 (91) 319  
 B (3TC/ABC/NNRTI throughout, ZDV until week 36) 24 (7) 301 (93) 325  
 C (3TC/ABC/ZDV throughout, NNRTI until week 36) 15 (5) 310 (95) 325 0.06
Randomization
 Clinical monitoring 35 (7) 449 (93) 484  
 Laboratory monitoring 34 (7) 451 (93) 485 0.89
  1. Values are n (row %) unless otherwise stated
  2. aIn those over 5 years
  3. 3TC Lamivudine, ABC Abacavir, EFV Efavirenz, IQR Interquartile range, JCRC Joint Clinical Research Centre, NNRTI Non-nucleoside reverse transcriptase inhibitor, NVP Nevirapine, PIDC Paediatric Infectious Diseases Clinic, ZDV Zidovudine